{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T18:58:34Z","timestamp":1790621914472,"version":"4.1.0"},"reference-count":39,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"264","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sci. Transl. Med."],"published-print":{"date-parts":[[2014,11,26]]},"abstract":"<jats:p>Patient-specific iPSCs were derived, corrected, and differentiated into human skin grafts for the treatment of recessive dystrophic epidermolysis bullosa.<\/jats:p>","DOI":"10.1126\/scitranslmed.3009540","type":"journal-article","created":{"date-parts":[[2014,11,26]],"date-time":"2014-11-26T15:51:35Z","timestamp":1417017095000},"source":"Crossref","is-referenced-by-count":203,"title":["Human\n                    <i>COL7A1<\/i>\n                    -corrected induced pluripotent stem cells for the treatment of recessive dystrophic epidermolysis bullosa"],"prefix":"10.1126","volume":"6","author":[{"given":"Vittorio","family":"Sebastiano","sequence":"first","affiliation":[{"name":"Institute for Stem Cell Biology and Regenerative Medicine, and Department of Pathology, Stanford University, Stanford, CA 94305, USA."},{"name":"Department of Obstetrics and Gynecology, Stanford University, Stanford, CA 94305, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanson Hui","family":"Zhen","sequence":"additional","affiliation":[{"name":"Program in Epithelial Biology, Department of Dermatology, Stanford University, Stanford, CA 94305, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bahareh","family":"Haddad","sequence":"additional","affiliation":[{"name":"Institute for Stem Cell Biology and Regenerative Medicine, and Department of Pathology, Stanford University, Stanford, CA 94305, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizaveta","family":"Bashkirova","sequence":"additional","affiliation":[{"name":"Institute for Stem Cell Biology and Regenerative Medicine, and Department of Pathology, Stanford University, Stanford, CA 94305, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra P.","family":"Melo","sequence":"additional","affiliation":[{"name":"Program in Epithelial Biology, Department of Dermatology, Stanford University, Stanford, CA 94305, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pei","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Developmental Biology, Stanford University, Stanford, CA 94305, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas L.","family":"Leung","sequence":"additional","affiliation":[{"name":"Department of Developmental Biology, Stanford University, Stanford, CA 94305, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zurab","family":"Siprashvili","sequence":"additional","affiliation":[{"name":"Program in Epithelial Biology, Department of Dermatology, Stanford University, Stanford, CA 94305, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Tichy","sequence":"additional","affiliation":[{"name":"Program in Epithelial Biology, Department of Dermatology, Stanford University, Stanford, CA 94305, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiang","family":"Li","sequence":"additional","affiliation":[{"name":"Program in Epithelial Biology, Department of Dermatology, Stanford University, Stanford, CA 94305, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed","family":"Ameen","sequence":"additional","affiliation":[{"name":"Program in Epithelial Biology, Department of Dermatology, Stanford University, Stanford, CA 94305, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Hawkins","sequence":"additional","affiliation":[{"name":"Institute for Stem Cell Biology and Regenerative Medicine, and Department of Pathology, Stanford University, Stanford, CA 94305, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susie","family":"Lee","sequence":"additional","affiliation":[{"name":"Program in Epithelial Biology, Department of Dermatology, Stanford University, Stanford, CA 94305, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingjie","family":"Li","sequence":"additional","affiliation":[{"name":"Program in Epithelial Biology, Department of Dermatology, Stanford University, Stanford, CA 94305, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aaron","family":"Schwertschkow","sequence":"additional","affiliation":[{"name":"Institute for Regenerative Cures, School of Medicine, University of California, Davis, Sacramento, CA 95817, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerhard","family":"Bauer","sequence":"additional","affiliation":[{"name":"Institute for Regenerative Cures, School of Medicine, University of California, Davis, Sacramento, CA 95817, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leszek","family":"Lisowski","sequence":"additional","affiliation":[{"name":"Departments of Pediatrics and Genetics, Stanford University, Stanford, CA 94305, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark A.","family":"Kay","sequence":"additional","affiliation":[{"name":"Departments of Pediatrics and Genetics, Stanford University, Stanford, CA 94305, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seung K.","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Developmental Biology, Stanford University, Stanford, CA 94305, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfred T.","family":"Lane","sequence":"additional","affiliation":[{"name":"Program in Epithelial Biology, Department of Dermatology, Stanford University, Stanford, CA 94305, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marius","family":"Wernig","sequence":"additional","affiliation":[{"name":"Institute for Stem Cell Biology and Regenerative Medicine, and Department of Pathology, Stanford University, Stanford, CA 94305, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony E.","family":"Oro","sequence":"additional","affiliation":[{"name":"Program in Epithelial Biology, Department of Dermatology, Stanford University, Stanford, CA 94305, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"221","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2014.01.903"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.det.2010.02.012"},{"key":"e_1_3_2_4_2","unstructured":"J. D. Fine L. B. Johnson C. Suchindran E. A. Bauer M. Carter J. McGuire A. Moshell in Epidermolysis Bullosa. Clinical Epidemiologic and Laboratory Advances and the Findings of the National Epidermolysis Bullosa Registry J. D. Fine E. A. Bauer J. McGuire A. Moshell Eds. (The Johns Hopkins University Press Baltimore MD 1999) pp. 175\u2013192."},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1038\/ng1041"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1089\/10430340260201743"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1089\/104303403765701204"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1038\/nm766"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddg200"},{"key":"e_1_3_2_10_2","first-page":"S75","article-title":"Phase I clinical trial of genetically corrected autologous epidermal keratinocytes for recessive dystrophic epidermolysis bullosa","volume":"134","author":"Siprashvili Z.","year":"2014","unstructured":"Siprashvili Z., Nguyen N., Gorell E., Khuu P., Furukawa L., Lorenz H., Leung T., Keene D., Khavari P., Marinkovich M., Lane A., Phase I clinical trial of genetically corrected autologous epidermal keratinocytes for recessive dystrophic epidermolysis bullosa. J. Invest. Dermatol. 134, S75 (2014).","journal-title":"J. Invest. Dermatol."},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-med-050311-163324"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/embj.201387098"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcibr1103052"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1002\/stem.718"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/stem.495"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2009.09118.x"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI30465"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.3009342"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2011.01.017"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.21948"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1038\/mt.2013.290"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-62703-761-7_16"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00204-012-0998-9"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)61496-3"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1100332108"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1038\/nm1504"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1634\/stemcells.2007-0501"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10544-014-9858-0"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2014.04.001"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1177\/1535370214530369"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-62703-128-8_32"},{"key":"e_1_3_2_32_2","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.3010083"},{"key":"e_1_3_2_33_2","first-page":"821","article-title":"Cultured skin substitutes reduce requirements for harvesting of skin autograft for closure of excised, full-thickness burns","volume":"60","author":"Boyce S. T.","year":"2006","unstructured":"Boyce S. T., Kagan R. J., Greenhalgh D. G., Warner P., Yakuboff K. P., Palmieri T., Warden G. D., Cultured skin substitutes reduce requirements for harvesting of skin autograft for closure of excised, full-thickness burns. J. Trauma 60, 821\u2013829 (2006).","journal-title":"J. Trauma"},{"key":"e_1_3_2_34_2","doi-asserted-by":"publisher","DOI":"10.1634\/stemcells.2008-1075"},{"key":"e_1_3_2_35_2","doi-asserted-by":"publisher","DOI":"10.1089\/ten.tea.2009.0325"},{"key":"e_1_3_2_36_2","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12284237"},{"key":"e_1_3_2_37_2","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2008.211"},{"key":"e_1_3_2_38_2","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btp324"},{"key":"e_1_3_2_39_2","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btp352"},{"key":"e_1_3_2_40_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkq603"}],"container-title":["Science Translational Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.science.org\/doi\/pdf\/10.1126\/scitranslmed.3009540","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,16]],"date-time":"2024-01-16T13:40:07Z","timestamp":1705412407000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.science.org\/doi\/10.1126\/scitranslmed.3009540"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,11,26]]},"references-count":39,"journal-issue":{"issue":"264","published-print":{"date-parts":[[2014,11,26]]}},"alternative-id":["10.1126\/scitranslmed.3009540"],"URL":"https:\/\/doi.org\/10.1126\/scitranslmed.3009540","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.725249033.793501988","asserted-by":"object"}]},"ISSN":["1946-6234","1946-6242"],"issn-type":[{"value":"1946-6234","type":"print"},{"value":"1946-6242","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,11,26]]}}}