{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T05:03:30Z","timestamp":1791090210321,"version":"4.1.0"},"reference-count":52,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"366","license":[{"start":{"date-parts":[[2017,11,23]],"date-time":"2017-11-23T00:00:00Z","timestamp":1511395200000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.sciencemag.org\/about\/science-licenses-journal-article-reuse"}],"funder":[{"DOI":"10.13039\/100000865","name":"Bill & Melinda Gates Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000865","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["DK30292"],"award-info":[{"award-number":["DK30292"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004440","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["96100"],"award-info":[{"award-number":["96100"]}],"id":[{"id":"10.13039\/100004440","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sci. Transl. Med."],"published-print":{"date-parts":[[2016,11,23]]},"abstract":"<jats:p>Pathobiont-associated cachexia in a gnotobiotic model of childhood undernutrition is determined by strain-level interactions within the gut microbiota.<\/jats:p>","DOI":"10.1126\/scitranslmed.aah4669","type":"journal-article","created":{"date-parts":[[2016,11,23]],"date-time":"2016-11-23T19:47:38Z","timestamp":1479930458000},"source":"Crossref","is-referenced-by-count":62,"title":["Effects of a gut pathobiont in a gnotobiotic mouse model of childhood undernutrition"],"prefix":"10.1126","volume":"8","author":[{"given":"Vitas E.","family":"Wagner","sequence":"first","affiliation":[{"name":"Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St. Louis, MO 63110, USA."},{"name":"Center for Gut Microbiome and Nutrition Research, Washington University School of Medicine, St. Louis, MO 63110, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neelendu","family":"Dey","sequence":"additional","affiliation":[{"name":"Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St. Louis, MO 63110, USA."},{"name":"Center for Gut Microbiome and Nutrition Research, Washington University School of Medicine, St. Louis, MO 63110, USA."},{"name":"Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janaki","family":"Guruge","sequence":"additional","affiliation":[{"name":"Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St. Louis, MO 63110, USA."},{"name":"Center for Gut Microbiome and Nutrition Research, Washington University School of Medicine, St. Louis, MO 63110, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ansel","family":"Hsiao","sequence":"additional","affiliation":[{"name":"Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St. Louis, MO 63110, USA."},{"name":"Center for Gut Microbiome and Nutrition Research, Washington University School of Medicine, St. Louis, MO 63110, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip P.","family":"Ahern","sequence":"additional","affiliation":[{"name":"Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St. Louis, MO 63110, USA."},{"name":"Center for Gut Microbiome and Nutrition Research, Washington University School of Medicine, St. Louis, MO 63110, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas P.","family":"Semenkovich","sequence":"additional","affiliation":[{"name":"Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St. Louis, MO 63110, USA."},{"name":"Center for Gut Microbiome and Nutrition Research, Washington University School of Medicine, St. Louis, MO 63110, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura V.","family":"Blanton","sequence":"additional","affiliation":[{"name":"Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St. Louis, MO 63110, USA."},{"name":"Center for Gut Microbiome and Nutrition Research, Washington University School of Medicine, St. Louis, MO 63110, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiye","family":"Cheng","sequence":"additional","affiliation":[{"name":"Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St. Louis, MO 63110, USA."},{"name":"Center for Gut Microbiome and Nutrition Research, Washington University School of Medicine, St. Louis, MO 63110, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas","family":"Griffin","sequence":"additional","affiliation":[{"name":"Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St. Louis, MO 63110, USA."},{"name":"Center for Gut Microbiome and Nutrition Research, Washington University School of Medicine, St. Louis, MO 63110, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thaddeus S.","family":"Stappenbeck","sequence":"additional","affiliation":[{"name":"Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olga","family":"Ilkayeva","sequence":"additional","affiliation":[{"name":"Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, NC 27710, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher B.","family":"Newgard","sequence":"additional","affiliation":[{"name":"Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, NC 27710, USA."},{"name":"Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC 27710, USA."},{"name":"Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA."},{"name":"Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William","family":"Petri","sequence":"additional","affiliation":[{"name":"Departments of Medicine, Microbiology, and Pathology, University of Virginia School of Medicine, Charlottesville, VA 22908, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rashidul","family":"Haque","sequence":"additional","affiliation":[{"name":"International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka 1212, Bangladesh."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tahmeed","family":"Ahmed","sequence":"additional","affiliation":[{"name":"International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka 1212, Bangladesh."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey I.","family":"Gordon","sequence":"additional","affiliation":[{"name":"Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St. Louis, MO 63110, USA."},{"name":"Center for Gut Microbiome and Nutrition Research, Washington University School of Medicine, St. Louis, MO 63110, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"221","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.semperi.2015.06.009"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(13)60937-X"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3016.2012.01298.x"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)61692-4"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature13421"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.aad3311"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1229000"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.aaa4877"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1753-4887.2008.00082.x"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0000000000000351"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI72334"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1086\/428947"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1086\/591130"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cir807"},{"key":"e_1_3_2_16_2","unstructured":"World Health Organization (WHO) WHO Child Growth Standards: Growth velocity based on weight length and head circumference: Methods and development. WHO (2009) www.who.int\/childgrowth\/standards\/velocity\/technical_report\/en\/."},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.3945\/jn.110.123059"},{"key":"e_1_3_2_18_2","unstructured":"S. N. Islam M. N. I. Khan M. Akhtaruzzaman A Food Composition Database for Bangladesh with Special reference to Selected Ethnic Foods (INFS-NFPCSP-FAO Dhaka Bangladesh 2010); www.nfpcsp.org\/agridrupal\/content\/food-composition-database-bangladesh-special-reference-selected-ethnic-foods."},{"key":"e_1_3_2_19_2","unstructured":"US Department of Agriculture (USDA) Agricultural Research Service Nutrient Data Laboratory USDA National Nutrient Database for Standard Reference Release 28 (2015); www.ars.usda.gov\/nea\/bhnrc\/ndl."},{"key":"e_1_3_2_20_2","first-page":"1","article-title":"Socioeconomic and demographic variation in nutritional status of under-five Bangladeshi children and trend over the twelve-year period 1996\u20132007","author":"Mohsena M.","year":"2016","unstructured":"Mohsena M., Goto R., Mascie-Taylor C. G. N., Socioeconomic and demographic variation in nutritional status of under-five Bangladeshi children and trend over the twelve-year period 1996\u20132007. J. Biosocial Sci., 1\u201317 (2016).","journal-title":"J. Biosocial Sci."},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1102938108"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2015.08.059"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.38.2.607-612.2000"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1038\/nm.4077"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biochem.6b00546"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1093\/biostatistics\/kxm030"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1271\/bbb.68.1758"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0809600106"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature13738"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2015.02.049"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2249.2002.01921.x"},{"key":"e_1_3_2_32_2","doi-asserted-by":"publisher","DOI":"10.1053\/gast.2003.50047"},{"key":"e_1_3_2_33_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00814-08"},{"key":"e_1_3_2_34_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid0602.000210"},{"key":"e_1_3_2_35_2","doi-asserted-by":"publisher","DOI":"10.1038\/nm.2015"},{"key":"e_1_3_2_36_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature07008"},{"key":"e_1_3_2_37_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0909122107"},{"key":"e_1_3_2_38_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.69.7.4342-4350.2001"},{"key":"e_1_3_2_39_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.aad9359"},{"key":"e_1_3_2_40_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature18849"},{"key":"e_1_3_2_41_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.37.3.801-803.1999"},{"key":"e_1_3_2_42_2","unstructured":"B. Chevreux T. Wetter S. Suhai Computer Science and Biology in Proceedings of the German Conference on Bioinformatics Hannover 4 to 6 October 1999 (GCB 1999) pp. 45\u201346."},{"key":"e_1_3_2_43_2","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btu153"},{"key":"e_1_3_2_44_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkr989"},{"key":"e_1_3_2_45_2","doi-asserted-by":"publisher","DOI":"10.1186\/gb-2004-5-2-r12"},{"key":"e_1_3_2_46_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1241214"},{"key":"e_1_3_2_47_2","doi-asserted-by":"publisher","DOI":"10.1128\/jb.165.3.929-936.1986"},{"key":"e_1_3_2_48_2","doi-asserted-by":"publisher","DOI":"10.1038\/nm995"},{"key":"e_1_3_2_49_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1000034"},{"key":"e_1_3_2_50_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M604350200"},{"key":"e_1_3_2_51_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2007.05.005"},{"key":"e_1_3_2_52_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymeth.2005.01.009"},{"key":"e_1_3_2_53_2","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.3008051"}],"container-title":["Science Translational Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.science.org\/doi\/pdf\/10.1126\/scitranslmed.aah4669","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,16]],"date-time":"2024-01-16T17:30:14Z","timestamp":1705426214000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.science.org\/doi\/10.1126\/scitranslmed.aah4669"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11,23]]},"references-count":52,"journal-issue":{"issue":"366","published-print":{"date-parts":[[2016,11,23]]}},"alternative-id":["10.1126\/scitranslmed.aah4669"],"URL":"https:\/\/doi.org\/10.1126\/scitranslmed.aah4669","relation":{},"ISSN":["1946-6234","1946-6242"],"issn-type":[{"value":"1946-6234","type":"print"},{"value":"1946-6242","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,11,23]]}}}