{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T01:17:57Z","timestamp":1768439877361,"version":"3.49.0"},"reference-count":10,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"437","license":[{"start":{"date-parts":[[2018,4,18]],"date-time":"2018-04-18T00:00:00Z","timestamp":1524009600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.sciencemag.org\/about\/science-licenses-journal-article-reuse"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sci. Transl. Med."],"published-print":{"date-parts":[[2018,4,18]]},"abstract":"<jats:p>\n            A key enzyme in cholesterol synthesis is placed firmly on the oncogenic map and demonstrated to be a potential therapeutic target in liver cancer by repurposing a common antifungal agent (Liu\n            <jats:italic>et al<\/jats:italic>\n            ., this issue).\n          <\/jats:p>","DOI":"10.1126\/scitranslmed.aat3741","type":"journal-article","created":{"date-parts":[[2018,4,18]],"date-time":"2018-04-18T18:06:38Z","timestamp":1524074798000},"source":"Crossref","is-referenced-by-count":13,"title":["Cholesterol, cancer, and rebooting a treatment for athlete\u2019s foot"],"prefix":"10.1126","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2785-2767","authenticated-orcid":true,"given":"Ngee Kiat","family":"Chua","sequence":"first","affiliation":[{"name":"School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, New South Wales 2052, Australia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hudson W.","family":"Coates","sequence":"additional","affiliation":[{"name":"School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, New South Wales 2052, Australia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4475-0116","authenticated-orcid":true,"given":"Andrew J.","family":"Brown","sequence":"additional","affiliation":[{"name":"School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, New South Wales 2052, Australia."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"221","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tem.2015.11.008"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.aap9840"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2011.01.015"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrm2336"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-16-0903"},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.1038\/srep19435"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-pathol-020117-043617"},{"key":"e_1_3_1_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2014.01.019"},{"key":"e_1_3_1_10_2","doi-asserted-by":"publisher","DOI":"10.1038\/ncb3551"},{"key":"e_1_3_1_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tem.2010.01.001"}],"container-title":["Science Translational Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.science.org\/doi\/pdf\/10.1126\/scitranslmed.aat3741","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,16]],"date-time":"2024-01-16T18:41:32Z","timestamp":1705430492000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.science.org\/doi\/10.1126\/scitranslmed.aat3741"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4,18]]},"references-count":10,"journal-issue":{"issue":"437","published-print":{"date-parts":[[2018,4,18]]}},"alternative-id":["10.1126\/scitranslmed.aat3741"],"URL":"https:\/\/doi.org\/10.1126\/scitranslmed.aat3741","relation":{},"ISSN":["1946-6234","1946-6242"],"issn-type":[{"value":"1946-6234","type":"print"},{"value":"1946-6242","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,4,18]]},"article-number":"eaat3741"}}