{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T00:15:40Z","timestamp":1791591340478,"version":"4.3.4"},"reference-count":34,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"490","funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["80001971"],"award-info":[{"award-number":["80001971"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000011","name":"Howard Hughes Medical Institute","doi-asserted-by":"publisher","award":["80005299"],"award-info":[{"award-number":["80005299"]}],"id":[{"id":"10.13039\/100000011","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Smilow Center for Marfan Research","award":["80001976"],"award-info":[{"award-number":["80001976"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sci. Transl. Med."],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:p>Protection from pregnancy-associated aortic dissection is achieved by decreasing oxytocin-induced ERK signaling in a mouse model of Marfan syndrome.<\/jats:p>","DOI":"10.1126\/scitranslmed.aat4822","type":"journal-article","created":{"date-parts":[[2019,5,1]],"date-time":"2019-05-01T19:40:20Z","timestamp":1556739620000},"source":"Crossref","is-referenced-by-count":65,"title":["Oxytocin antagonism prevents pregnancy-associated aortic dissection in a mouse model of Marfan syndrome"],"prefix":"10.1126","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6779-670X","authenticated-orcid":true,"given":"Jennifer Pardo","family":"Habashi","sequence":"first","affiliation":[{"name":"Division of Pediatric Cardiology, Johns Hopkins University, Baltimore, MD 21287, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5677-6842","authenticated-orcid":true,"given":"Elena Gallo","family":"MacFarlane","sequence":"additional","affiliation":[{"name":"Center for Medical Genetics, Johns Hopkins University, Baltimore, MD 21287, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rustam","family":"Bagirzadeh","sequence":"additional","affiliation":[{"name":"Center for Medical Genetics, Johns Hopkins University, Baltimore, MD 21287, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0218-9885","authenticated-orcid":true,"given":"Caitlin","family":"Bowen","sequence":"additional","affiliation":[{"name":"Center for Medical Genetics, Johns Hopkins University, Baltimore, MD 21287, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6451-5503","authenticated-orcid":true,"given":"Nicholas","family":"Huso","sequence":"additional","affiliation":[{"name":"Center for Medical Genetics, Johns Hopkins University, Baltimore, MD 21287, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9092-7189","authenticated-orcid":true,"given":"Yichun","family":"Chen","sequence":"additional","affiliation":[{"name":"Center for Medical Genetics, Johns Hopkins University, Baltimore, MD 21287, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Djahida","family":"Bedja","sequence":"additional","affiliation":[{"name":"Division of Comparative Medicine, Johns Hopkins University, Baltimore, MD 21287, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1872-5248","authenticated-orcid":true,"given":"Tyler J.","family":"Creamer","sequence":"additional","affiliation":[{"name":"Department of Surgery, Johns Hopkins University, Baltimore, MD 21287, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0918-3926","authenticated-orcid":true,"given":"Graham","family":"Rykiel","sequence":"additional","affiliation":[{"name":"Center for Medical Genetics, Johns Hopkins University, Baltimore, MD 21287, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maurice","family":"Manning","sequence":"additional","affiliation":[{"name":"Department of Cancer Biology, University of Toledo College of Medicine, Toledo, OH 43614, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Huso","sequence":"additional","affiliation":[{"name":"Division of Comparative Medicine, Johns Hopkins University, Baltimore, MD 21287, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6856-0165","authenticated-orcid":true,"given":"Harry C.","family":"Dietz","sequence":"additional","affiliation":[{"name":"Center for Medical Genetics, Johns Hopkins University, Baltimore, MD 21287, USA."},{"name":"Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"221","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2009.01.073"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.104.493569"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-123-2-199507150-00007"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehi103"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-2115(03)00151-9"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2008.04.035"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e3182107310"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.116.004052"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.14635"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1038\/ng1116"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1124287"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1192152"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1161\/ATVBAHA.114.305150"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1192149"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/cge.12436"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.humrep.a137484"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.3109\/00016349009036151"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.110137497"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsgi.2004.11.008"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1006\/bbrc.1996.1905"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00042.2004"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.96.7.3819"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2826.2012.02303.x"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.93.21.11699"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.08648"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.114.005129"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2017.05.055"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-5381.1986.tb14595.x"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.00390.2010"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M106457200"},{"key":"e_1_3_2_32_2","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.91588"},{"key":"e_1_3_2_33_2","doi-asserted-by":"publisher","DOI":"10.1016\/0741-5214(92)90101-D"},{"key":"e_1_3_2_34_2","doi-asserted-by":"publisher","DOI":"10.1042\/CS20090372"},{"key":"e_1_3_2_35_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.physbeh.2011.10.025"}],"container-title":["Science Translational Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1126\/scitranslmed.aat4822","content-type":"unspecified","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.science.org\/doi\/pdf\/10.1126\/scitranslmed.aat4822","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,16]],"date-time":"2024-01-16T12:52:09Z","timestamp":1705409529000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.science.org\/doi\/10.1126\/scitranslmed.aat4822"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5]]},"references-count":34,"journal-issue":{"issue":"490","published-print":{"date-parts":[[2019,5]]}},"alternative-id":["10.1126\/scitranslmed.aat4822"],"URL":"https:\/\/doi.org\/10.1126\/scitranslmed.aat4822","relation":{},"ISSN":["1946-6234","1946-6242"],"issn-type":[{"value":"1946-6234","type":"print"},{"value":"1946-6242","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,5]]},"article-number":"eaat4822"}}