{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T01:38:09Z","timestamp":1792805889934,"version":"4.5.0"},"reference-count":82,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"539","funder":[{"DOI":"10.13039\/501100000781","name":"European Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000781","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011747","name":"Novo Nordisk Foundation Center for Basic Metabolic Research","doi-asserted-by":"publisher","award":["Laureate Program"],"award-info":[{"award-number":["Laureate Program"]}],"id":[{"id":"10.13039\/501100011747","id-type":"DOI","asserted-by":"publisher"}]},{"name":"L\u00e6ge Sofus Carl Emil Friis og hustru Olga Doris Friis\u2019 Legat"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sci. Transl. Med."],"published-print":{"date-parts":[[2020,4,15]]},"abstract":"<jats:p>\n                    Prolonged treatment with nimodipine soon after spinal cord injury in mice prevents spasticity by blocking L-type calcium channels Ca\n                    <jats:sub>V<\/jats:sub>\n                    1.3.\n                  <\/jats:p>","DOI":"10.1126\/scitranslmed.aay0167","type":"journal-article","created":{"date-parts":[[2020,4,15]],"date-time":"2020-04-15T19:07:49Z","timestamp":1586977669000},"source":"Crossref","is-referenced-by-count":44,"title":["Early delivery and prolonged treatment with nimodipine prevents the development of spasticity after spinal cord injury in mice"],"prefix":"10.1126","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6665-5251","authenticated-orcid":true,"given":"Maite","family":"Marcantoni","sequence":"first","affiliation":[{"name":"Department of Neuroscience, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen Denmark."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Fuchs","sequence":"additional","affiliation":[{"name":"Department of Neuroscience, Karolinska Institutet, 17162 Solna, Sweden."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1948-0951","authenticated-orcid":true,"given":"Peter","family":"L\u00f6w","sequence":"additional","affiliation":[{"name":"Department of Neuroscience, Karolinska Institutet, 17162 Solna, Sweden."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1140-9923","authenticated-orcid":true,"given":"Dusan","family":"Bartsch","sequence":"additional","affiliation":[{"name":"Transgenic Models, Central Institute of Mental Health, 28159 Mannheim, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5954-469X","authenticated-orcid":true,"given":"Ole","family":"Kiehn","sequence":"additional","affiliation":[{"name":"Department of Neuroscience, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen Denmark."},{"name":"Department of Neuroscience, Karolinska Institutet, 17162 Solna, Sweden."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6198-243X","authenticated-orcid":true,"given":"Carmelo","family":"Bellardita","sequence":"additional","affiliation":[{"name":"Department of Neuroscience, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen Denmark."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"221","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2017.18"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrneurol.2009.227"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1038\/sc.2016.46"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(07)70193-X"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1038\/sc.2010.145"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmr.2008.07.012"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2011.08.025"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-018-0649-2"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.sc.3101757"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-4598(1997)6 <92::AID-MUS7>3.0.CO;2-E"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1989.sp017687"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00236.2003"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1460-9568.2000.00055.x"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1152\/jn.2001.86.4.1972"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.23011"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1111\/bph.13747"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1124\/pr.114.009654"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2012.00060"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1089\/cns.1985.2.109"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00227945"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(81)90976-8"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2008.09.002"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.conb.2010.03.013"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.21769\/BioProtoc.2784"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1089\/neu.1999.16.69"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1089\/cell.2009.0093"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1089\/neu.1992.9.219"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1038\/nm.2160"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)30668-7"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.2165\/00003495-198937050-00004"},{"key":"e_1_3_2_32_2","doi-asserted-by":"publisher","DOI":"10.1080\/10641960802580232"},{"key":"e_1_3_2_33_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1157.1992.tb02358.x"},{"key":"e_1_3_2_34_2","doi-asserted-by":"publisher","DOI":"10.1152\/jn.01104.2007"},{"key":"e_1_3_2_35_2","doi-asserted-by":"publisher","DOI":"10.1080\/16501960310010142"},{"key":"e_1_3_2_36_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)00013-1"},{"key":"e_1_3_2_37_2","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/dds217"},{"key":"e_1_3_2_38_2","doi-asserted-by":"publisher","DOI":"10.1002\/dvg.20656"},{"key":"e_1_3_2_39_2","doi-asserted-by":"publisher","DOI":"10.1038\/srep41054"},{"key":"e_1_3_2_40_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mcn.2010.06.016"},{"key":"e_1_3_2_41_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1304365110"},{"key":"e_1_3_2_42_2","doi-asserted-by":"publisher","DOI":"10.1038\/srep41369"},{"key":"e_1_3_2_43_2","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00918.2010"},{"key":"e_1_3_2_44_2","doi-asserted-by":"publisher","DOI":"10.1152\/jn.01111.2009"},{"key":"e_1_3_2_45_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1460-9568.2000.00050.x"},{"key":"e_1_3_2_46_2","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a003947"},{"key":"e_1_3_2_47_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.2003586"},{"key":"e_1_3_2_48_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0501331102"},{"key":"e_1_3_2_49_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2017.09.076"},{"key":"e_1_3_2_50_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1620052114"},{"key":"e_1_3_2_51_2","doi-asserted-by":"publisher","DOI":"10.1038\/nn1703"},{"key":"e_1_3_2_52_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-9993(99)90329-5"},{"key":"e_1_3_2_53_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmr.2016.09.124"},{"key":"e_1_3_2_54_2","doi-asserted-by":"publisher","DOI":"10.1615\/CritRevPhysRehabilMed.2013007945"},{"key":"e_1_3_2_55_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature09536"},{"key":"e_1_3_2_56_2","doi-asserted-by":"publisher","DOI":"10.1111\/jnc.14324"},{"key":"e_1_3_2_57_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2017.01.048"},{"key":"e_1_3_2_58_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2016.09.026"},{"key":"e_1_3_2_59_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0099-5428(04)31011-7"},{"key":"e_1_3_2_60_2","doi-asserted-by":"publisher","DOI":"10.1089\/neu.2016.4513"},{"key":"e_1_3_2_61_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00236551"},{"key":"e_1_3_2_62_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.20261"},{"key":"e_1_3_2_63_2","doi-asserted-by":"publisher","DOI":"10.1038\/ng.2695"},{"key":"e_1_3_2_64_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ceca.2009.08.006"},{"key":"e_1_3_2_65_2","doi-asserted-by":"publisher","DOI":"10.1113\/JP270672"},{"key":"e_1_3_2_66_2","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.15744"},{"key":"e_1_3_2_67_2","doi-asserted-by":"publisher","DOI":"10.1038\/nm.4061"},{"key":"e_1_3_2_68_2","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.35222"},{"key":"e_1_3_2_69_2","doi-asserted-by":"publisher","DOI":"10.1007\/s13311-011-0031-7"},{"key":"e_1_3_2_70_2","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.1996.76.2.319"},{"key":"e_1_3_2_71_2","doi-asserted-by":"publisher","DOI":"10.1096\/fj.04-1805fje"},{"key":"e_1_3_2_72_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.conb.2016.12.005"},{"key":"e_1_3_2_73_2","doi-asserted-by":"publisher","DOI":"10.1038\/nm.4331"},{"key":"e_1_3_2_74_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0306-4522(00)00165-2"},{"key":"e_1_3_2_75_2","first-page":"425","article-title":"An L-type calcium channel blocker, nimodipine influences trauma induced spinal cord conduction and axonal injury in the rat","volume":"86","author":"Winkler T.","year":"2003","unstructured":"T. Winkler, H. S. Sharma, E. Stalberg, R. D. Badgaiyan, T. Gordh, J. Westman, An L-type calcium channel blocker, nimodipine influences trauma induced spinal cord conduction and axonal injury in the rat. Acta Neurochir. Suppl. 86, 425\u2013432 (2003).","journal-title":"Acta Neurochir. Suppl."},{"key":"e_1_3_2_76_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-018-0467-6"},{"key":"e_1_3_2_77_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2013.12.024"},{"key":"e_1_3_2_78_2","doi-asserted-by":"publisher","DOI":"10.4238\/2015.February.13.5"},{"key":"e_1_3_2_79_2","doi-asserted-by":"publisher","DOI":"10.1089\/neu.1993.10.201"},{"key":"e_1_3_2_80_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4992-13.2014"},{"key":"e_1_3_2_81_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2015.04.005"},{"key":"e_1_3_2_82_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature25448"},{"key":"e_1_3_2_83_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuint.2016.07.003"}],"container-title":["Science Translational Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1126\/scitranslmed.aay0167","content-type":"unspecified","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.science.org\/doi\/pdf\/10.1126\/scitranslmed.aay0167","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,16]],"date-time":"2024-01-16T12:45:05Z","timestamp":1705409105000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.science.org\/doi\/10.1126\/scitranslmed.aay0167"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,4,15]]},"references-count":82,"journal-issue":{"issue":"539","published-print":{"date-parts":[[2020,4,15]]}},"alternative-id":["10.1126\/scitranslmed.aay0167"],"URL":"https:\/\/doi.org\/10.1126\/scitranslmed.aay0167","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/639211","asserted-by":"object"}]},"ISSN":["1946-6234","1946-6242"],"issn-type":[{"value":"1946-6234","type":"print"},{"value":"1946-6242","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,4,15]]},"article-number":"eaay0167"}}