{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T22:04:40Z","timestamp":1791497080596,"version":"4.3.4"},"reference-count":57,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"566","funder":[{"DOI":"10.13039\/100013279","name":"Joint Programming Initiative A healthy diet for a healthy life","doi-asserted-by":"publisher","award":["ANR-15-HDIM-0001-1"],"award-info":[{"award-number":["ANR-15-HDIM-0001-1"]}],"id":[{"id":"10.13039\/100013279","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100013279","name":"Joint Programming Initiative A healthy diet for a healthy life","doi-asserted-by":"publisher","award":["JPI-HDHL 50-52905-98-601"],"award-info":[{"award-number":["JPI-HDHL 50-52905-98-601"]}],"id":[{"id":"10.13039\/100013279","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["CIHR-143922"],"award-info":[{"award-number":["CIHR-143922"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["168840"],"award-info":[{"award-number":["168840"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sci. Transl. Med."],"published-print":{"date-parts":[[2020,10,21]]},"abstract":"<jats:p>Impaired AhR ligand production by the gut microbiota decreases AhR pathway activation, promoting inflammation in celiac disease.<\/jats:p>","DOI":"10.1126\/scitranslmed.aba0624","type":"journal-article","created":{"date-parts":[[2020,10,21]],"date-time":"2020-10-21T19:12:18Z","timestamp":1603307538000},"source":"Crossref","is-referenced-by-count":178,"title":["Aryl hydrocarbon receptor ligand production by the gut microbiota is decreased in celiac disease leading to intestinal inflammation"],"prefix":"10.1126","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7777-2127","authenticated-orcid":true,"given":"Bruno","family":"Lamas","sequence":"first","affiliation":[{"name":"Farncombe Family Digestive Health Research Institute, Department of Medicine, McMaster University, Hamilton, Ontario, Canada."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leticia","family":"Hernandez-Galan","sequence":"additional","affiliation":[{"name":"Farncombe Family Digestive Health Research Institute, Department of Medicine, McMaster University, Hamilton, Ontario, Canada."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6413-0803","authenticated-orcid":true,"given":"Heather J.","family":"Galipeau","sequence":"additional","affiliation":[{"name":"Farncombe Family Digestive Health Research Institute, Department of Medicine, McMaster University, Hamilton, Ontario, Canada."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7448-5552","authenticated-orcid":true,"given":"Marco","family":"Constante","sequence":"additional","affiliation":[{"name":"Farncombe Family Digestive Health Research Institute, Department of Medicine, McMaster University, Hamilton, Ontario, Canada."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0672-5956","authenticated-orcid":true,"given":"Alexandra","family":"Clarizio","sequence":"additional","affiliation":[{"name":"Farncombe Family Digestive Health Research Institute, Department of Medicine, McMaster University, Hamilton, Ontario, Canada."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0028-4691","authenticated-orcid":true,"given":"Jennifer","family":"Jury","sequence":"additional","affiliation":[{"name":"Farncombe Family Digestive Health Research Institute, Department of Medicine, McMaster University, Hamilton, Ontario, Canada."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2109-9332","authenticated-orcid":true,"given":"Natalia M.","family":"Breyner","sequence":"additional","affiliation":[{"name":"Farncombe Family Digestive Health Research Institute, Department of Medicine, McMaster University, Hamilton, Ontario, Canada."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9555-7167","authenticated-orcid":true,"given":"Alberto","family":"Caminero","sequence":"additional","affiliation":[{"name":"Farncombe Family Digestive Health Research Institute, Department of Medicine, McMaster University, Hamilton, Ontario, Canada."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaston","family":"Rueda","sequence":"additional","affiliation":[{"name":"Farncombe Family Digestive Health Research Institute, Department of Medicine, McMaster University, Hamilton, Ontario, Canada."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9055-2391","authenticated-orcid":true,"given":"Christina L.","family":"Hayes","sequence":"additional","affiliation":[{"name":"Farncombe Family Digestive Health Research Institute, Department of Medicine, McMaster University, Hamilton, Ontario, Canada."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justin L.","family":"McCarville","sequence":"additional","affiliation":[{"name":"Farncombe Family Digestive Health Research Institute, Department of Medicine, McMaster University, Hamilton, Ontario, Canada."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miriam","family":"Bermudez Brito","sequence":"additional","affiliation":[{"name":"Farncombe Family Digestive Health Research Institute, Department of Medicine, McMaster University, Hamilton, Ontario, Canada."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3427-7425","authenticated-orcid":true,"given":"Julien","family":"Planchais","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris-Saclay, INRAE, AgroParisTech, Micalis Institute, 78350, Jouy-en-Josas, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathalie","family":"Rolhion","sequence":"additional","affiliation":[{"name":"Sorbonne Universit\u00e9, Inserm, Centre de Recherche Saint-Antoine, CRSA, AP-HP, H\u00f4pital Saint Antoine, Service de Gastroenterologie, F-75012 Paris, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph A.","family":"Murray","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, Department of Immunology, Mayo Clinic College of Medicine, Rochester, MN, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Langella","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris-Saclay, INRAE, AgroParisTech, Micalis Institute, 78350, Jouy-en-Josas, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0935-2494","authenticated-orcid":true,"given":"Linda M. P.","family":"Loonen","sequence":"additional","affiliation":[{"name":"Host-Microbe Interactomics, Animal Sciences Group, Wageningen University, Wageningen, Netherlands."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jerry M.","family":"Wells","sequence":"additional","affiliation":[{"name":"Host-Microbe Interactomics, Animal Sciences Group, Wageningen University, Wageningen, Netherlands."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8707-1781","authenticated-orcid":true,"given":"Premysl","family":"Bercik","sequence":"additional","affiliation":[{"name":"Farncombe Family Digestive Health Research Institute, Department of Medicine, McMaster University, Hamilton, Ontario, Canada."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2914-1822","authenticated-orcid":true,"given":"Harry","family":"Sokol","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris-Saclay, INRAE, AgroParisTech, Micalis Institute, 78350, Jouy-en-Josas, France."},{"name":"Sorbonne Universit\u00e9, Inserm, Centre de Recherche Saint-Antoine, CRSA, AP-HP, H\u00f4pital Saint Antoine, Service de Gastroenterologie, F-75012 Paris, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6346-2665","authenticated-orcid":true,"given":"Elena F.","family":"Verdu","sequence":"additional","affiliation":[{"name":"Farncombe Family Digestive Health Research Institute, Department of Medicine, McMaster University, Hamilton, Ontario, Canada."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"221","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1313977"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrgastro.2015.90"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajpath.2015.07.018"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.aah5298"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1601247"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2016.11.046"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1038\/nri3430"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41575-018-0064-z"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2016.06.041"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-09037-9"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1223813"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1101\/gad.284091.116"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2018.05.003"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41385-018-0019-2"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2013.08.003"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1002\/mnfr.201800722"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-05470-4"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1038\/mp.2012.77"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2015.02.047"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2019.00091"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.47410-0"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2014.355"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2016.95"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1038\/nm.4102"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2018.07.001"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/9351507"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tibtech.2015.06.011"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.2174\/092986711795656072"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2014.09.001"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41577-019-0125-8"},{"key":"e_1_3_2_32_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clim.2013.02.012"},{"key":"e_1_3_2_33_2","doi-asserted-by":"publisher","DOI":"10.1038\/mi.2010.36"},{"key":"e_1_3_2_34_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2011.09.025"},{"key":"e_1_3_2_35_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1004492107"},{"key":"e_1_3_2_36_2","doi-asserted-by":"publisher","DOI":"10.1097\/MOG.0b013e32835c9cb3"},{"key":"e_1_3_2_37_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2249.2007.03365.x"},{"key":"e_1_3_2_38_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-immunol-032713-120245"},{"key":"e_1_3_2_39_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2019.02.028"},{"key":"e_1_3_2_40_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.aah5825"},{"key":"e_1_3_2_41_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.resmic.2017.04.008"},{"key":"e_1_3_2_42_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-019-0899-7"},{"key":"e_1_3_2_43_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2011.04.007"},{"key":"e_1_3_2_44_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature21080"},{"key":"e_1_3_2_45_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2013.08.002"},{"key":"e_1_3_2_46_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20082683"},{"key":"e_1_3_2_47_2","doi-asserted-by":"publisher","DOI":"10.1038\/ni.2025"},{"key":"e_1_3_2_48_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0020749"},{"key":"e_1_3_2_49_2","doi-asserted-by":"publisher","DOI":"10.1038\/nri3365"},{"key":"e_1_3_2_50_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.0900233"},{"key":"e_1_3_2_51_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-020-2003-8"},{"key":"e_1_3_2_52_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1100854"},{"key":"e_1_3_2_53_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.talanta.2018.11.094"},{"key":"e_1_3_2_54_2","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2018-317232"},{"key":"e_1_3_2_55_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2018.06.012"},{"key":"e_1_3_2_56_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-018-0060-4"},{"key":"e_1_3_2_57_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2017.01809"},{"key":"e_1_3_2_58_2","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.f.303"}],"container-title":["Science Translational Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1126\/scitranslmed.aba0624","content-type":"unspecified","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.science.org\/doi\/pdf\/10.1126\/scitranslmed.aba0624","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,16]],"date-time":"2024-01-16T13:21:16Z","timestamp":1705411276000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.science.org\/doi\/10.1126\/scitranslmed.aba0624"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10,21]]},"references-count":57,"journal-issue":{"issue":"566","published-print":{"date-parts":[[2020,10,21]]}},"alternative-id":["10.1126\/scitranslmed.aba0624"],"URL":"https:\/\/doi.org\/10.1126\/scitranslmed.aba0624","relation":{},"ISSN":["1946-6234","1946-6242"],"issn-type":[{"value":"1946-6234","type":"print"},{"value":"1946-6242","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,10,21]]},"article-number":"eaba0624"}}