{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T04:18:13Z","timestamp":1791001093385,"version":"4.1.0"},"reference-count":75,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"591","funder":[{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["R35HL135805"],"award-info":[{"award-number":["R35HL135805"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["HL145152"],"award-info":[{"award-number":["HL145152"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000057","name":"National Institute of General Medical Sciences","doi-asserted-by":"publisher","award":["R01RGM131642"],"award-info":[{"award-number":["R01RGM131642"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sci. Transl. Med."],"published-print":{"date-parts":[[2021,4,28]]},"abstract":"<jats:p>MAP3K inhibition attenuates acute lung injuries in mice and reduced edema in lung transplantation recipients.<\/jats:p>","DOI":"10.1126\/scitranslmed.abc2499","type":"journal-article","created":{"date-parts":[[2021,10,8]],"date-time":"2021-10-08T19:38:27Z","timestamp":1633721907000},"source":"Crossref","is-referenced-by-count":16,"title":["Pazopanib ameliorates acute lung injuries via inhibition of MAP3K2 and MAP3K3"],"prefix":"10.1126","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4972-3264","authenticated-orcid":true,"given":"Qianying","family":"Yuan","sequence":"first","affiliation":[{"name":"Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT 06520, USA."},{"name":"Department of Pharmacology, Yale University School of Medicine, New Haven, CT 06520, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7881-806X","authenticated-orcid":true,"given":"Abdul","family":"Basit","sequence":"additional","affiliation":[{"name":"Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT 06520, USA."},{"name":"Department of Pharmacology, Yale University School of Medicine, New Haven, CT 06520, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1391-8238","authenticated-orcid":true,"given":"Wenhua","family":"Liang","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery\/Oncology, First Affiliated Hospital of Guangzhou Medical University, China State Key Laboratory of Respiratory Disease and National Clinical Research Center for Respiratory Disease, Guangzhou 510120, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8258-8287","authenticated-orcid":true,"given":"Rihao","family":"Qu","sequence":"additional","affiliation":[{"name":"Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA."},{"name":"Department of Pathology, Yale University School of Medicine, New Haven, CT 06520, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3044-6700","authenticated-orcid":true,"given":"Yi","family":"Luan","sequence":"additional","affiliation":[{"name":"Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT 06520, USA."},{"name":"Department of Pharmacology, Yale University School of Medicine, New Haven, CT 06520, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3245-1159","authenticated-orcid":true,"given":"Chunguang","family":"Ren","sequence":"additional","affiliation":[{"name":"Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT 06520, USA."},{"name":"Department of Pharmacology, Yale University School of Medicine, New Haven, CT 06520, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ao","family":"Li","sequence":"additional","affiliation":[{"name":"Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT 06520, USA."},{"name":"Department of Pharmacology, Yale University School of Medicine, New Haven, CT 06520, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4834-7922","authenticated-orcid":true,"given":"Xin","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery\/Oncology, First Affiliated Hospital of Guangzhou Medical University, China State Key Laboratory of Respiratory Disease and National Clinical Research Center for Respiratory Disease, Guangzhou 510120, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3059-7293","authenticated-orcid":true,"given":"Xiaoqing","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery\/Oncology, First Affiliated Hospital of Guangzhou Medical University, China State Key Laboratory of Respiratory Disease and National Clinical Research Center for Respiratory Disease, Guangzhou 510120, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6148-0237","authenticated-orcid":true,"given":"Chun","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery\/Oncology, First Affiliated Hospital of Guangzhou Medical University, China State Key Laboratory of Respiratory Disease and National Clinical Research Center for Respiratory Disease, Guangzhou 510120, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7263-8658","authenticated-orcid":true,"given":"Andrew","family":"Kuo","sequence":"additional","affiliation":[{"name":"Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT 06520, USA."},{"name":"Department of Pharmacology, Yale University School of Medicine, New Haven, CT 06520, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5941-8805","authenticated-orcid":true,"given":"Richard","family":"Pierce","sequence":"additional","affiliation":[{"name":"Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT 06520, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9077-3239","authenticated-orcid":true,"given":"Longbo","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Yale University School of Medicine, New Haven, CT 06520, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9275-4069","authenticated-orcid":true,"given":"Benjamin","family":"Turk","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, Yale University School of Medicine, New Haven, CT 06520, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1097-3300","authenticated-orcid":true,"given":"Xin","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, Yale University School of Medicine, New Haven, CT 06520, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3171-7592","authenticated-orcid":true,"given":"Fangyong","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, Yale University School of Medicine, New Haven, CT 06520, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2146-6208","authenticated-orcid":true,"given":"Weixue","family":"Cui","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery\/Oncology, First Affiliated Hospital of Guangzhou Medical University, China State Key Laboratory of Respiratory Disease and National Clinical Research Center for Respiratory Disease, Guangzhou 510120, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9505-2713","authenticated-orcid":true,"given":"Run","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery\/Oncology, First Affiliated Hospital of Guangzhou Medical University, China State Key Laboratory of Respiratory Disease and National Clinical Research Center for Respiratory Disease, Guangzhou 510120, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9505-2713","authenticated-orcid":true,"given":"Danxia","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery\/Oncology, First Affiliated Hospital of Guangzhou Medical University, China State Key Laboratory of Respiratory Disease and National Clinical Research Center for Respiratory Disease, Guangzhou 510120, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3030-7225","authenticated-orcid":true,"given":"Lili","family":"Mo","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery\/Oncology, First Affiliated Hospital of Guangzhou Medical University, China State Key Laboratory of Respiratory Disease and National Clinical Research Center for Respiratory Disease, Guangzhou 510120, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5759-1938","authenticated-orcid":true,"given":"William C.","family":"Sessa","sequence":"additional","affiliation":[{"name":"Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT 06520, USA."},{"name":"Department of Pharmacology, Yale University School of Medicine, New Haven, CT 06520, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9906-1628","authenticated-orcid":true,"given":"Patty J.","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Medicine, Yale University School of Medicine, New Haven, CT 06520, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3035-071X","authenticated-orcid":true,"given":"Yuval","family":"Kluger","sequence":"additional","affiliation":[{"name":"Department of Pathology, Yale University School of Medicine, New Haven, CT 06520, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0871-7666","authenticated-orcid":true,"given":"Bing","family":"Su","sequence":"additional","affiliation":[{"name":"Shanghai Institute of Immunology, Shanghai Jiaotong University, Shanghai 200025, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9234-4385","authenticated-orcid":true,"given":"Wenwen","family":"Tang","sequence":"additional","affiliation":[{"name":"Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT 06520, USA."},{"name":"Department of Pharmacology, Yale University School of Medicine, New Haven, CT 06520, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1737-8192","authenticated-orcid":true,"given":"Jianxing","family":"He","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery\/Oncology, First Affiliated Hospital of Guangzhou Medical University, China State Key Laboratory of Respiratory Disease and National Clinical Research Center for Respiratory Disease, Guangzhou 510120, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7342-5961","authenticated-orcid":true,"given":"Dianqing","family":"Wu","sequence":"additional","affiliation":[{"name":"Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT 06520, USA."},{"name":"Department of Pharmacology, Yale University School of Medicine, New Haven, CT 06520, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"221","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1089\/jamp.2009.0775"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.4187\/respcare.04716"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200005043421801"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200205-478OC"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-pathol-011110-130158"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.12688\/f1000research.9691.1"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1038\/nri3399"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2009.2590"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(03)00314-3"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2016.00311"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2362.2012.02720.x"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2010.05552.x"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.168.8.3974"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.69.10.5991-5996.2001"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.172.3.1801"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.0902315"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1096\/fj.02-0331com"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.72.10.5722-5732.2004"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2008.12.003"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.2353\/ajpath.2008.070765"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200707-990OC"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.2000.278.6.L1240"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M503292200"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.185.2.207"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.177.8.5509"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1002\/eji.200635977"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0009631"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200806-851OC"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00618.2006"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2015-05-644773"},{"key":"e_1_3_2_32_2","doi-asserted-by":"publisher","DOI":"10.1002\/eji.200636651"},{"key":"e_1_3_2_33_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.172.1.636"},{"key":"e_1_3_2_34_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00281-008-0119-2"},{"key":"e_1_3_2_35_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.emboj.7600913"},{"key":"e_1_3_2_36_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2011.01.017"},{"key":"e_1_3_2_37_2","doi-asserted-by":"publisher","DOI":"10.1038\/73550"},{"key":"e_1_3_2_38_2","doi-asserted-by":"publisher","DOI":"10.1038\/89769"},{"key":"e_1_3_2_39_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1002127"},{"key":"e_1_3_2_40_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2567.2006.02495.x"},{"key":"e_1_3_2_41_2","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms8937"},{"key":"e_1_3_2_42_2","doi-asserted-by":"publisher","DOI":"10.1038\/ni1008-1091"},{"key":"e_1_3_2_43_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-1759(96)00236-0"},{"key":"e_1_3_2_44_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200103013440908"},{"key":"e_1_3_2_45_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkg584"},{"key":"e_1_3_2_46_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V99.8.2653"},{"key":"e_1_3_2_47_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M509249200"},{"key":"e_1_3_2_48_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tem.2014.06.012"},{"key":"e_1_3_2_49_2","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00501.2008"},{"key":"e_1_3_2_50_2","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200706072"},{"key":"e_1_3_2_51_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.277.5323.242"},{"key":"e_1_3_2_52_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.114.007512"},{"key":"e_1_3_2_53_2","doi-asserted-by":"publisher","DOI":"10.4161\/cam.28495"},{"key":"e_1_3_2_54_2","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1242\/jcs.179960","article-title":"VE-cadherin facilitates BMP-induced endothelial cell permeability and signaling","volume":"129","author":"Benn A.","year":"2016","unstructured":"A. Benn, C. Bredow, I. Casanova, S. Vukicevic, P. Knaus, VE-cadherin facilitates BMP-induced endothelial cell permeability and signaling. J. Cell Sci. 129, 206\u2013218 (2016).","journal-title":"J. Cell Sci."},{"key":"e_1_3_2_55_2","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2012-3462"},{"key":"e_1_3_2_56_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0156002"},{"key":"e_1_3_2_57_2","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.91700"},{"key":"e_1_3_2_58_2","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.24633"},{"key":"e_1_3_2_59_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)81270-2"},{"key":"e_1_3_2_60_2","doi-asserted-by":"publisher","DOI":"10.1242\/dev.124.20.3943"},{"key":"e_1_3_2_61_2","doi-asserted-by":"publisher","DOI":"10.1242\/dev.161976"},{"key":"e_1_3_2_62_2","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201007-1157OC"},{"key":"e_1_3_2_63_2","doi-asserted-by":"publisher","DOI":"10.1177\/1087057112466430"},{"key":"e_1_3_2_64_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2015.06.029"},{"key":"e_1_3_2_65_2","first-page":"443","article-title":"Pazopanib: The newest tyrosine kinase inhibitor for the treatment of advanced or metastatic renal cell carcinoma","volume":"71","author":"Keisner S. V.","year":"2011","unstructured":"S. V. Keisner, S. R. Shah, Pazopanib: The newest tyrosine kinase inhibitor for the treatment of advanced or metastatic renal cell carcinoma. Drugs 71, 443\u2013454 (2011).","journal-title":"Drugs"},{"key":"e_1_3_2_66_2","doi-asserted-by":"publisher","DOI":"10.21037\/jtd.2017.09.09"},{"key":"e_1_3_2_67_2","doi-asserted-by":"publisher","DOI":"10.1242\/dmm.006213"},{"key":"e_1_3_2_68_2","doi-asserted-by":"publisher","DOI":"10.1517\/14740338.2012.712108"},{"key":"e_1_3_2_69_2","doi-asserted-by":"publisher","DOI":"10.1161\/ATVBAHA.110.203901"},{"key":"e_1_3_2_70_2","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.114.7.1343"},{"key":"e_1_3_2_71_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1602006"},{"key":"e_1_3_2_72_2","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.22.16.5761-5768.2002"},{"key":"e_1_3_2_73_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.0803738"},{"key":"e_1_3_2_74_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2019.12.038"},{"key":"e_1_3_2_75_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-5381.2010.00920.x"},{"key":"e_1_3_2_76_2","doi-asserted-by":"publisher","DOI":"10.1165\/rcmb.2009-0210ST"}],"container-title":["Science Translational Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.science.org\/doi\/pdf\/10.1126\/scitranslmed.abc2499","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,9]],"date-time":"2024-09-09T15:32:37Z","timestamp":1725895957000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.science.org\/doi\/10.1126\/scitranslmed.abc2499"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4,28]]},"references-count":75,"journal-issue":{"issue":"591","published-print":{"date-parts":[[2021,4,28]]}},"alternative-id":["10.1126\/scitranslmed.abc2499"],"URL":"https:\/\/doi.org\/10.1126\/scitranslmed.abc2499","relation":{},"ISSN":["1946-6234","1946-6242"],"issn-type":[{"value":"1946-6234","type":"print"},{"value":"1946-6242","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,4,28]]},"article-number":"eabc2499"}}