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The spread of desensitization away from the injection site suggests that calcium ion can diffuse over neuronal dimensions, but that the effective rate of diffusion is not so high as to abolish calcium gradients. The results are compatible with the previously proposed hypothesis that a rise in the intracellular calcium ion concentration mediates light adaptation.\n          <\/jats:p>","DOI":"10.1126\/science.1114339","type":"journal-article","created":{"date-parts":[[2006,10,5]],"date-time":"2006-10-05T15:11:22Z","timestamp":1160061082000},"page":"1094-1096","source":"Crossref","is-referenced-by-count":41,"title":["Localized Desensitization of\n            <i>Limulus<\/i>\n            Photoreceptors Produced by Light or Intracellular Calcium Ion Injection"],"prefix":"10.1126","volume":"187","author":[{"given":"A.","family":"Fein","sequence":"first","affiliation":[]},{"given":"J.","family":"Lisman","sequence":"additional","affiliation":[]}],"member":"221","reference":[{"key":"e_1_2_1_1_1","first-page":"456","volume":"143","year":"1972","unstructured":"BROWN, J. 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