{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T04:36:36Z","timestamp":1776141396080,"version":"3.50.1"},"reference-count":29,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"5038","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Science"],"published-print":{"date-parts":[[1991,12,13]]},"abstract":"<jats:p>\n            The integral membrane protein porin from\n            <jats:italic>Rhodobacter capsulatus<\/jats:italic>\n            consists of three tightly associated 16-stranded \u03b2 barrels that give rise to three distinct diffusion channels for small solutes through the outer membrane. The x-ray structure of this porin has revealed details of its shape, the residue distributions within the pore and at the membrane-facing surface, and the location of calcium sites. The electrostatic potential has been calculated and related to function. Moreover, potential calculations were found to predict the Ca\n            <jats:sup>2+<\/jats:sup>\n            sites.\n          <\/jats:p>","DOI":"10.1126\/science.1721242","type":"journal-article","created":{"date-parts":[[2006,10,5]],"date-time":"2006-10-05T22:10:16Z","timestamp":1160086216000},"page":"1627-1630","source":"Crossref","is-referenced-by-count":562,"title":["Molecular Architecture and Electrostatic Properties of a Bacterial Porin"],"prefix":"10.1126","volume":"254","author":[{"given":"M. S.","family":"Weiss","sequence":"first","affiliation":[{"name":"Institut f\u00fcr Organische Chemie und Biochemie, Freiburg, Federal Republic of Germany."}]},{"given":"U.","family":"Abele","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Organische Chemie und Biochemie, Freiburg, Federal Republic of Germany."}]},{"given":"J.","family":"Weckesser","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Biologic II, Mikrobiologie Schanzlestrasse 1, D-7800 Freiburg im Breisgau, Federal Republic of Germany."}]},{"given":"W.","family":"Welte","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Biophysik und Strahlenbiologie, Albertstrasse 23, D-7800 Freiburg im Breisgau, Federal Republic of Germany"}]},{"given":"E.","family":"Schiltz","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Organische Chemie und Biochemie, Freiburg, Federal Republic of Germany."}]},{"given":"G. 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