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It is not yet clear whether the pathogenesis in this disease relates to polyglutamine inclusions or to dysfunction of the ion channel ["},{"key":"e_1_3_1_53_3","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1038\/ng0197-62","volume":"15","author":"Zhuchenko O.","year":"1997","unstructured":"Zhuchenko O., et al., Nature Genet. 15, 62 (1997)].","journal-title":"Nature Genet."},{"key":"e_1_3_1_54_2","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1038\/ng0997-65","volume":"17","author":"David G.","year":"1997","unstructured":"David G., et al., Nature Genet. 17, 65 (1997);","journal-title":"Nature Genet."},{"key":"e_1_3_1_54_3","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1093\/hmg\/7.5.913","volume":"7","author":"Holberg M.","year":"1998","unstructured":"Holberg M., et al., Hum. Mol. Genet. 7, 913 (1998).","journal-title":"Hum. Mol. Genet."},{"key":"e_1_3_1_55_2","unstructured":"We thank D. Dickson for his help and encouragement and for the figures. Work in the authors' laboratory was funded by the NIA (Mayo\/USF Program Project grant) and by the Mayo Foundation."}],"container-title":["Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.science.org\/doi\/pdf\/10.1126\/science.282.5391.1075","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,13]],"date-time":"2024-01-13T05:16:38Z","timestamp":1705122998000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.science.org\/doi\/10.1126\/science.282.5391.1075"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,11,6]]},"references-count":110,"journal-issue":{"issue":"5391","published-print":{"date-parts":[[1998,11,6]]}},"alternative-id":["10.1126\/science.282.5391.1075"],"URL":"https:\/\/doi.org\/10.1126\/science.282.5391.1075","relation":{},"ISSN":["0036-8075","1095-9203"],"issn-type":[{"value":"0036-8075","type":"print"},{"value":"1095-9203","type":"electronic"}],"subject":[],"published":{"date-parts":[[1998,11,6]]}}}