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Transformed marrow cells injected into irradiated and methotrexate-treated recipient mice gave rise to proliferating cells which in some cases dominated the marrow population and which contained HSVtk gene sequences.\n          <\/jats:p>","DOI":"10.1126\/science.6246577","type":"journal-article","created":{"date-parts":[[2006,10,5]],"date-time":"2006-10-05T17:45:58Z","timestamp":1160070358000},"page":"1033-1035","source":"Crossref","is-referenced-by-count":78,"title":["Insertion of a New Gene of Viral Origin into Bone Marrow Cells of Mice"],"prefix":"10.1126","volume":"208","author":[{"given":"Karen E.","family":"Mercola","sequence":"first","affiliation":[{"name":"Department of Medicine, University of California at Los Angeles, Los Angeles 90024"}]},{"given":"Howard D.","family":"Stang","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of California at Los Angeles, Los Angeles 90024"}]},{"given":"Jeffrey","family":"Browne","sequence":"additional","affiliation":[{"name":"Department of Biology, University of California at Los Angeles, Los Angeles 90024"},{"name":"Molecular Biology Institute, University of California at Los Angeles, Los Angeles 90024"}]},{"given":"Winston","family":"Salser","sequence":"additional","affiliation":[{"name":"Department of Biology, University of California at Los Angeles, Los Angeles 90024"}]},{"given":"Martin J.","family":"Cline","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of California at Los Angeles, Los Angeles 90024"},{"name":"Molecular Biology Institute, University of California at Los Angeles, Los Angeles 90024"}]}],"member":"221","reference":[{"key":"e_1_2_1_1_1","first-page":"1590","volume":"74","year":"1977","unstructured":"BACHETTI, S, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 74: 1590 (1977).","journal-title":"PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA"},{"key":"e_1_2_1_2_1","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1038\/284422a0","volume":"284","year":"1980","unstructured":"CLINE, M.J., GENE-TRANSFER IN INTACT ANIMALS, NATURE 284: 422 (1980).","journal-title":"NATURE"},{"key":"e_1_2_1_3_1","first-page":"3755","volume":"76","year":"1979","unstructured":"COLBEREGARAPIN, F, CLONING OF THE ACTIVE THYMIDINE KINASE GENE OF HERPES-SIMPLEX VIRUS TYPE-1 IN ESCHERICHIA-COLI K-12, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 76: 3755 (1979).","journal-title":"PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.216076"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.74.1.319"},{"key":"e_1_2_1_6_1","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/0092-8674(77)90334-8","volume":"11","year":"1977","unstructured":"MAITLAND, N.J., BIOCHEMICAL TRANSFORMATION OF MOUSE CELLS BY FRAGMENTS OF HERPES-SIMPLEX VIRUS-DNA, CELL 11: 233 (1977).","journal-title":"CELL"},{"key":"e_1_2_1_7_1","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1038\/281040a0","volume":"281","year":"1979","unstructured":"MANTEI, N, RABBIT BETA-GLOBIN MESSENGER-RNA PRODUCTION IN MOUSE L-CELLS TRANSFORMED WITH CLONED RABBIT BETA-GLOBIN CHROMOSOMAL DNA, NATURE 281: 40 (1979).","journal-title":"NATURE"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.7.6.813-820.1971"},{"key":"e_1_2_1_9_1","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/0092-8674(78)90308-2","volume":"14","year":"1978","unstructured":"PELLICER, A, TRANSFER AND STABLE INTEGRATION OF HSV THYMIDINE KINASE GENE INTO MOUSE CELLS, CELL 14: 133 (1978).","journal-title":"CELL"},{"key":"e_1_2_1_10_1","unstructured":"SALSER W UNPUBLISHED."},{"key":"e_1_2_1_11_1","first-page":"847","volume":"40","year":"1968","unstructured":"SMITH, W.W., KINETICS OF STEM CELL DEPLETION AND PROLIFERATION - 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