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Serum V\n            <jats:sub>H<\/jats:sub>\n            3 IgM from uninfected individuals also avidly bound gp120. Finally, gp120 selectively induced Ig secretion by V\n            <jats:sub>H<\/jats:sub>\n            3 B cells, indicating that the binding of gp120 functionally activated these cells. These results indicate that naturally occurring V\n            <jats:sub>H<\/jats:sub>\n            3 Ig is a second ligand for gp120 and a candidate superantigen for V\n            <jats:sub>H<\/jats:sub>\n            3 B cells.\n          <\/jats:p>","DOI":"10.1126\/science.7690497","type":"journal-article","created":{"date-parts":[[2006,10,5]],"date-time":"2006-10-05T23:05:09Z","timestamp":1160089509000},"page":"1588-1591","source":"Crossref","is-referenced-by-count":206,"title":["Immunoglobulin V\n            <sub>H<\/sub>\n            3 Gene Products: Natural Ligands for HIV gp120"],"prefix":"10.1126","volume":"261","author":[{"given":"Linda","family":"Berberian","sequence":"first","affiliation":[{"name":"Department of Pathology and Laboratory Medicine, University of California, Los Angeles, CA 90024."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lee","family":"Goodglick","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine, University of California, Los Angeles, CA 90024."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas J.","family":"Kipps","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of California at San Diego, La Jolla, CA 92093."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan","family":"Braun","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine, University of California, Los Angeles, CA 90024."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"221","reference":[{"key":"e_1_2_1_1_1","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1016\/0167-5699(90)90144-X","volume":"11","year":"1990","unstructured":"AMADORI, A, B-CELL ACTIVATION AND HIV-1 INFECTION - 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