{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T18:50:26Z","timestamp":1792090226549,"version":"4.4.0"},"reference-count":56,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"6821","funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32372554"],"award-info":[{"award-number":["32372554"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["RS-2025-02213915\/RS-2025-25455550"],"award-info":[{"award-number":["RS-2025-02213915\/RS-2025-25455550"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"name":"National Key Research and Development Projec","award":["2023YFE0123400"],"award-info":[{"award-number":["2023YFE0123400"]}]},{"name":"Key Laboratory of Agricultural and Forestry Biosecurity","award":["SKLJRP2510"],"award-info":[{"award-number":["SKLJRP2510"]}]}],"content-domain":{"domain":["www.science.org"],"crossmark-restriction":true},"short-container-title":["Science"],"published-print":{"date-parts":[[2026,10,15]]},"abstract":"<jats:p>\n                    Chitosan, a major fungal cell wall component, activates plant immunity, yet the underlying perception mechanism remains unknown. In this study, we identified OsFID1, an apoplast-localized DUF26 domain protein, as a chitosan-binding receptor essential for chitosan-triggered immunity. OsFID1 forms a receptor complex with OsFID2, a plasma membrane\u2013localized DUF26 receptor-like kinase, to mediate chitosan sensing and immune activation, requiring OsFID2 phosphorylation for function. The OsFID1-OsFID2 complex confers broad-spectrum resistance to fungal pathogens. OsFID1 homologs are conserved in land plants, which show chitosan-binding activity in both monocots and dicots. Ectopic expression of\n                    <jats:italic toggle=\"yes\">OsFID1<\/jats:italic>\n                    in wheat and maize enhanced fungal resistance without growth penalty. These findings uncover a conserved receptor complex for direct chitosan sensing, advancing our understanding of plant-fungus interactions and providing a potential strategy for engineering durable fungal resistance crops.\n                  <\/jats:p>","DOI":"10.1126\/science.ady7647","type":"journal-article","created":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T18:03:06Z","timestamp":1792087386000},"page":"291-297","update-policy":"https:\/\/doi.org\/10.34133\/aaas_crossmark","source":"Crossref","is-referenced-by-count":0,"title":["A pair of chitosan receptors confer broad-spectrum fungal resistance"],"prefix":"10.1126","volume":"394","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-4093-2710","authenticated-orcid":true,"given":"Keyi","family":"Huang","sequence":"first","affiliation":[{"name":"State Key Laboratory of Agricultural and Forestry Biosecurity, College of Plant Protection, Nanjing Agricultural University, Nanjing, 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