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Ceftobiprole also bound well to PBP2 in the latter organisms, contributing to the broad-spectrum antibacterial activity against gram-negative and gram-positive bacteria.\n                  <\/jats:p>","DOI":"10.1128\/aac.00029-07","type":"journal-article","created":{"date-parts":[[2007,4,30]],"date-time":"2007-04-30T21:05:03Z","timestamp":1177967103000},"page":"2621-2624","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":150,"title":["Binding of Ceftobiprole and Comparators to the Penicillin-Binding Proteins of\n                    <i>Escherichia coli<\/i>\n                    ,\n                    <i>Pseudomonas aeruginosa<\/i>\n                    ,\n                    <i>Staphylococcus aureus<\/i>\n                    , and\n                    <i>Streptococcus pneumoniae<\/i>"],"prefix":"10.1128","volume":"51","author":[{"given":"Todd A.","family":"Davies","sequence":"first","affiliation":[{"name":"Johnson &amp; Johnson Pharmaceutical Research and Development, LLC, Raritan, New Jersey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Malcolm G. 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