{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T01:27:38Z","timestamp":1792286858555,"version":"4.4.0"},"reference-count":26,"publisher":"American Society for Microbiology","issue":"8","license":[{"start":{"date-parts":[[2012,8,1]],"date-time":"2012-08-01T00:00:00Z","timestamp":1343779200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2012,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            We sought to define the prevalence of\n            <jats:italic>blaZ<\/jats:italic>\n            gene types and the inoculum effect to cefazolin among methicillin-susceptible\n            <jats:named-content xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" content-type=\"genus-species\" xlink:type=\"simple\">Staphylococcus aureus<\/jats:named-content>\n            (MSSA) bloodstream infections. The\n            <jats:italic>blaZ<\/jats:italic>\n            gene was present in 142\/185 (77%) isolates. A total of 50 (27%) isolates had a \u22654-fold increase in the cefazolin MIC from a standard to a high inoculum, and 8 (4%) demonstrated a nonsusceptible cefazolin MIC, all type A\n            <jats:italic>blaZ<\/jats:italic>\n            strains. The efficacy of cefazolin in the presence of the inoculum effect requires further study.\n          <\/jats:p>","DOI":"10.1128\/aac.00052-12","type":"journal-article","created":{"date-parts":[[2012,5,15]],"date-time":"2012-05-15T05:40:21Z","timestamp":1337060421000},"page":"4474-4477","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":55,"title":["Prevalence of\n            <i>blaZ<\/i>\n            Gene Types and the Inoculum Effect with Cefazolin among Bloodstream Isolates of Methicillin-Susceptible Staphylococcus aureus"],"prefix":"10.1128","volume":"56","author":[{"given":"D. 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