{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:28:49Z","timestamp":1787016529625,"version":"build-2736575974"},"reference-count":26,"publisher":"American Society for Microbiology","issue":"4","license":[{"start":{"date-parts":[[2024,4,3]],"date-time":"2024-04-03T00:00:00Z","timestamp":1712102400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,4,3]],"date-time":"2024-04-03T00:00:00Z","timestamp":1712102400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"DOI":"10.13039\/501100021856","name":"Ministero dell'Universit\u00e0 e della Ricerca","doi-asserted-by":"crossref","award":["PRIN 2022 Prot. 20224BYR59"],"award-info":[{"award-number":["PRIN 2022 Prot. 20224BYR59"]}],"id":[{"id":"10.13039\/501100021856","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100008385","name":"Fondazione per la Ricerca sulla Fibrosi Cistica","doi-asserted-by":"crossref","award":["FFC#10\/2023"],"award-info":[{"award-number":["FFC#10\/2023"]}],"id":[{"id":"10.13039\/501100008385","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100021856","name":"Ministero dell'Universit\u00e0 e della Ricerca","doi-asserted-by":"crossref","award":["PRIN 2020 Prot. 20208LLXEJ"],"award-info":[{"award-number":["PRIN 2020 Prot. 20208LLXEJ"]}],"id":[{"id":"10.13039\/501100021856","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100021856","name":"Ministero dell'Universit\u00e0 e della Ricerca","doi-asserted-by":"crossref","award":["PRIN 2020 Prot. 202089LLEH, PRIN 2022 Prot. 2022C5PNXB"],"award-info":[{"award-number":["PRIN 2020 Prot. 202089LLEH, PRIN 2022 Prot. 2022C5PNXB"]}],"id":[{"id":"10.13039\/501100021856","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100009880","name":"Regione Lazio","doi-asserted-by":"crossref","award":["Gruppi di Ricerca 2020 POR. A0375E0026"],"award-info":[{"award-number":["Gruppi di Ricerca 2020 POR. A0375E0026"]}],"id":[{"id":"10.13039\/501100009880","id-type":"DOI","asserted-by":"crossref"}]},{"name":"European Union NextGenerationEU","award":["Rome Technopole CUP F83B22000040006"],"award-info":[{"award-number":["Rome Technopole CUP F83B22000040006"]}]},{"name":"European Union NextGenerationEU","award":["Rome Technopole CUP B53C20040570005"],"award-info":[{"award-number":["Rome Technopole CUP B53C20040570005"]}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2024,4,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title\/>\n                    <jats:p>\n                      Hydrogen sulfide (H\n                      <jats:sub>2<\/jats:sub>\n                      S) has been proposed to protect bacteria from antibiotics, pointing to H\n                      <jats:sub>2<\/jats:sub>\n                      S-producing enzymes as possible targets for the development of antibiotic adjuvants. Here, MIC assays performed with\n                      <jats:italic>Pseudomonas aeruginosa<\/jats:italic>\n                      mutants producing altered H\n                      <jats:sub>2<\/jats:sub>\n                      S levels demonstrate that H\n                      <jats:sub>2<\/jats:sub>\n                      S does not affect antibiotic resistance in this bacterium. Moreover, correlation analyses in a large collection of\n                      <jats:italic>P. aeruginosa<\/jats:italic>\n                      cystic fibrosis isolates argue against the protective role of H\n                      <jats:sub>2<\/jats:sub>\n                      S from antibiotic activity during chronic lung infection.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1128\/aac.00075-24","type":"journal-article","created":{"date-parts":[[2024,3,6]],"date-time":"2024-03-06T09:00:55Z","timestamp":1709715655000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":13,"title":["Hydrogen sulfide production does not affect antibiotic resistance in\n                    <i>Pseudomonas aeruginosa<\/i>"],"prefix":"10.1128","volume":"68","author":[{"given":"Lorenzo","family":"Caruso","sequence":"first","affiliation":[{"name":"Department of Science, University Roma Tre, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"Mellini","sequence":"additional","affiliation":[{"name":"Department of Science, University Roma Tre, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ortensia","family":"Catalano Gonzaga","sequence":"additional","affiliation":[{"name":"Department of Science, University Roma Tre, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandra","family":"Astegno","sequence":"additional","affiliation":[{"name":"Department of Biotechnology, University of Verona, Verona, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Forte","sequence":"additional","affiliation":[{"name":"Department of Biochemical Sciences, Sapienza University of Rome, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adele","family":"Di Matteo","sequence":"additional","affiliation":[{"name":"CNR Institute of Molecular Biology and Pathology, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Giuffr\u00e8","sequence":"additional","affiliation":[{"name":"CNR Institute of Molecular Biology and Pathology, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6128-7039","authenticated-orcid":false,"given":"Paolo","family":"Visca","sequence":"additional","affiliation":[{"name":"Department of Science, University Roma Tre, Rome, Italy"},{"name":"IRCCS Fondazione Santa Lucia, Rome, Italy"},{"name":"NBFC, National Biodiversity Future Center, Palermo, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5080-5665","authenticated-orcid":false,"given":"Francesco","family":"Imperi","sequence":"additional","affiliation":[{"name":"Department of Science, University Roma Tre, Rome, Italy"},{"name":"IRCCS Fondazione Santa Lucia, Rome, Italy"},{"name":"NBFC, National Biodiversity Future Center, Palermo, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Livia","family":"Leoni","sequence":"additional","affiliation":[{"name":"Department of Science, University Roma Tre, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1735-8565","authenticated-orcid":false,"given":"Giordano","family":"Rampioni","sequence":"additional","affiliation":[{"name":"Department of Science, University Roma Tre, Rome, Italy"},{"name":"IRCCS Fondazione Santa Lucia, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41579-022-00820-y"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(17)30753-3"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/cbdd.12478"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mib.2014.06.017"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2023.106845"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1209855"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/mmi.14593"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.3390\/antiox10081285"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1128\/mbio.01936-22"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.abd8377"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijms242216331"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chembiol.2020.10.012"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1134\/S0026893322050120"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(22)02185-7"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2017.00039"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1038\/ismej.2017.125"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1128\/jb.178.5.1310-1319.1996"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1128\/spectrum.00961-22"},{"key":"e_1_3_3_20_2","volume-title":"Bailey and Scott\u2019s diagnostic microbiology","author":"Forbes BA","year":"1998","unstructured":"Forbes BA, Sahm DF, Weissfeld AS. 1998. Bailey and Scott\u2019s diagnostic microbiology. 10th ed. Mosby Inc.","edition":"10"},{"key":"e_1_3_3_21_2","volume-title":"Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically","author":"Clinical and Laboratory Standards Institute","year":"2012","unstructured":"Clinical and Laboratory Standards Institute. 2012. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically. 9th ed. CLSI (Approved standard M07- A9), Wayne PA.","edition":"9"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00040-09"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1038\/ng.3148"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2019.00049"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2022.845231"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00602-18"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2020.01875"}],"container-title":["Antimicrobial Agents and Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/aac.00075-24","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/aac.00075-24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,3]],"date-time":"2024-04-03T09:12:53Z","timestamp":1712135573000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/aac.00075-24"}},"subtitle":[],"editor":[{"given":"Boudewijn L.","family":"de Jonge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2024,4,3]]},"references-count":26,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,4,3]]}},"alternative-id":["10.1128\/aac.00075-24"],"URL":"https:\/\/doi.org\/10.1128\/aac.00075-24","relation":{},"ISSN":["0066-4804","1098-6596"],"issn-type":[{"value":"0066-4804","type":"print"},{"value":"1098-6596","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4,3]]},"assertion":[{"value":"2024-01-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-02-18","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-03-06","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e00075-24"}}