{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T09:35:00Z","timestamp":1773221700510,"version":"3.50.1"},"reference-count":12,"publisher":"American Society for Microbiology","issue":"8","license":[{"start":{"date-parts":[[2007,8,1]],"date-time":"2007-08-01T00:00:00Z","timestamp":1185926400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2007,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            A new natural IND-type metallo-\u03b2-lactamase variant, IND-5, was identified in a clinical isolate of\n            <jats:italic>Chryseobacterium indologenes<\/jats:italic>\n            . IND-5 shared 92.8% and 92.4% amino acid homology with IND-1 and IND-3, respectively. Purified enzyme (pI = 8.8,\n            <jats:italic>M<\/jats:italic>\n            <jats:sub>r<\/jats:sub>\n            = 25,000) was able to hydrolyze penicillins, some narrow- and expanded-spectrum cephalosporins, and carbapenems but not monobactams.\n          <\/jats:p>","DOI":"10.1128\/aac.00083-07","type":"journal-article","created":{"date-parts":[[2007,5,1]],"date-time":"2007-05-01T01:05:03Z","timestamp":1177981503000},"page":"2988-2990","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":18,"title":["Identification and Characterization of a New Metallo-\u03b2-Lactamase, IND-5, from a Clinical Isolate of\n            <i>Chryseobacterium indologenes<\/i>"],"prefix":"10.1128","volume":"51","author":[{"given":"Mariagrazia","family":"Perilli","sequence":"first","affiliation":[{"name":"Dipartimento di Scienze e Tecnologie Biomediche, Universita\u0300 di L'Aquila, I-67100 L'Aquila"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bibiana","family":"Caporale","sequence":"additional","affiliation":[{"name":"Dipartimento di Scienze e Tecnologie Biomediche, Universita\u0300 di L'Aquila, I-67100 L'Aquila"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Celenza","sequence":"additional","affiliation":[{"name":"Dipartimento di Scienze e Tecnologie Biomediche, Universita\u0300 di L'Aquila, I-67100 L'Aquila"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristina","family":"Pellegrini","sequence":"additional","affiliation":[{"name":"Dipartimento di Scienze e Tecnologie Biomediche, Universita\u0300 di L'Aquila, I-67100 L'Aquila"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean Denis","family":"Docquier","sequence":"additional","affiliation":[{"name":"Dipartimento di Biologia Molecolare, Laboratorio di Fisiologia e Biotecnologia dei Microrganismi, Universita\u0300 di Siena, I-53100 Siena"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marilina","family":"Mezzatesta","sequence":"additional","affiliation":[{"name":"Dipartimento di Scienze Microbiologiche e Ginecologiche, Universita\u0300 di Catania, I-95124 Catania, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gian Maria","family":"Rossolini","sequence":"additional","affiliation":[{"name":"Dipartimento di Biologia Molecolare, Laboratorio di Fisiologia e Biotecnologia dei Microrganismi, Universita\u0300 di Siena, I-53100 Siena"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefania","family":"Stefani","sequence":"additional","affiliation":[{"name":"Dipartimento di Scienze Microbiologiche e Ginecologiche, Universita\u0300 di Catania, I-95124 Catania, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gianfranco","family":"Amicosante","sequence":"additional","affiliation":[{"name":"Dipartimento di Scienze e Tecnologie Biomediche, Universita\u0300 di L'Aquila, I-67100 L'Aquila"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.44.11.3028-3034.2000"},{"key":"e_1_3_2_3_2","unstructured":"Performance standards for antimicrobial susceptibility testing 2005"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/0006-2952(87)90609-5"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1038\/227680a0"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0691.2002.00401.x"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.41.11.2374"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-5793(98)01689-5"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.41.2.223"},{"key":"e_1_3_2_10_2","unstructured":"Molecular cloning: a laboratory manual 2001"},{"key":"e_1_3_2_11_2","first-page":"749","year":"2003","unstructured":"Schreckenberger, P. C., M. I. Daneshvar, R. S. Weyant, and D. G. Hollis. 2003. Acinetobacter,Achromobacter,Cryseobacterium,Moraxella, and other nonfermentative gram-negative rods, p. 749-779. In P. R. Murray, E. J. Baron, J. H. Jorgensen, M. A. Pfaller, and R. H. Yolken (ed.), Manual of clinical microbiology, 8th ed. American Society for Microbiology, Washington, DC.","journal-title":"Manual of clinical microbiology"},{"key":"e_1_3_2_12_2","first-page":"210","year":"1975","unstructured":"Segel, I. H. 1975. Enzyme kinetics, behavior and analysis of rapid equilibrium and steady-state enzyme systems, p. 210-212. John Wiley & Sons, Inc., New York, NY.","journal-title":"Enzyme kinetics, behavior and analysis of rapid equilibrium and steady-state enzyme systems"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.18.2.306-325.2005"}],"container-title":["Antimicrobial Agents and Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.00083-07","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.00083-07","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,21]],"date-time":"2022-02-21T19:22:15Z","timestamp":1645471335000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/AAC.00083-07"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,8]]},"references-count":12,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2007,8]]}},"alternative-id":["10.1128\/AAC.00083-07"],"URL":"https:\/\/doi.org\/10.1128\/aac.00083-07","relation":{},"ISSN":["0066-4804","1098-6596"],"issn-type":[{"value":"0066-4804","type":"print"},{"value":"1098-6596","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,8]]},"assertion":[{"value":"2007-01-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2007-04-20","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2007-08-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}