{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T19:02:05Z","timestamp":1778612525465,"version":"3.51.4"},"reference-count":33,"publisher":"American Society for Microbiology","issue":"6","license":[{"start":{"date-parts":[[2018,6,1]],"date-time":"2018-06-01T00:00:00Z","timestamp":1527811200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"name":"CAMS Innovation Fund for Medical Sciences","award":["2016-I2M-1-014"],"award-info":[{"award-number":["2016-I2M-1-014"]}]},{"name":"National Key Research and Development Program of China","award":["2016YFC0901500"],"award-info":[{"award-number":["2016YFC0901500"]}]},{"name":"Beijing Innovation Base Cultivation and Development Special Fund","award":["Z171100002217068"],"award-info":[{"award-number":["Z171100002217068"]}]},{"DOI":"10.13039\/501100004543","name":"China Scholarship Council","doi-asserted-by":"crossref","award":["201706210414"],"award-info":[{"award-number":["201706210414"]}],"id":[{"id":"10.13039\/501100004543","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2018,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            Among 158\n            <jats:named-content content-type=\"genus-species\">Candida glabrata<\/jats:named-content>\n            bloodstream isolates collected from numerous centers in China, a resistance to fluconazole was seen in 8.9%. Three isolates (1.9%) were resistant to all echinocandins. Multilocus sequence typing (MLST) revealed that sequence type 7 ([ST7] 65.8%) was the most common type, followed by ST3 (7.6%).\n            <jats:italic>PDR1<\/jats:italic>\n            polymorphisms were associated with the acquisition of fluconazole resistance in\n            <jats:named-content content-type=\"genus-species\">C. glabrata<\/jats:named-content>\n            isolates, while\n            <jats:italic>MSH2<\/jats:italic>\n            polymorphisms were associated with the STs and microsatellite genotypes, irrespective of fluconazole resistance.\n          <\/jats:p>","DOI":"10.1128\/aac.00153-18","type":"journal-article","created":{"date-parts":[[2018,3,22]],"date-time":"2018-03-22T10:02:38Z","timestamp":1521712958000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":39,"title":["Profiling of\n            <i>PDR1<\/i>\n            and\n            <i>MSH2<\/i>\n            in Candida glabrata Bloodstream Isolates from a Multicenter Study in China"],"prefix":"10.1128","volume":"62","author":[{"given":"Xin","family":"Hou","sequence":"first","affiliation":[{"name":"Department of Clinical Laboratory, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China"},{"name":"Graduate School, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China"},{"name":"Beijing Key Laboratory for Mechanisms Research and Precision Diagnosis of Invasive Fungal Diseases (BZ0447), Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meng","family":"Xiao","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China"},{"name":"Beijing Key Laboratory for Mechanisms Research and Precision Diagnosis of Invasive Fungal Diseases (BZ0447), Beijing, 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