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Using a previously well-characterized case of malaria treatment failure, we show the utility of using next-generation sequencing for early detection of the rise and selection of a previously reported atovaquone-proguanil (malarone) drug resistance-associated mutation.<\/jats:p>","DOI":"10.1128\/aac.00171-16","type":"journal-article","created":{"date-parts":[[2016,3,22]],"date-time":"2016-03-22T03:45:36Z","timestamp":1458618336000},"page":"3821-3823","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":16,"title":["Advanced Molecular Detection of Malarone Resistance"],"prefix":"10.1128","volume":"60","author":[{"given":"Eldin","family":"Talundzic","sequence":"first","affiliation":[{"name":"Malaria Branch, Division of Parasitic Diseases and Malaria, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia, USA"},{"name":"Atlanta Research and Education Foundation, Veterans Affairs Medical 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