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Thioridazine might block these efflux pumps. We explore the efficacy of thioridazine against\n            <jats:named-content content-type=\"genus-species\">M. avium<\/jats:named-content>\n            isolates using MICs, time-kill combination assays,\n            <jats:italic>ex vivo<\/jats:italic>\n            macrophage infection assays, and efflux assays. Thioridazine is bactericidal against\n            <jats:named-content content-type=\"genus-species\">M. avium<\/jats:named-content>\n            , inhibits intracellular growth at 2\u00d7 MIC, and blocks ethidium bromide efflux.\n          <\/jats:p>","DOI":"10.1128\/aac.00181-20","type":"journal-article","created":{"date-parts":[[2020,4,15]],"date-time":"2020-04-15T14:37:58Z","timestamp":1586961478000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":16,"title":["Thioridazine Is an Efflux Pump Inhibitor in Mycobacterium avium Complex but of Limited Clinical Relevance"],"prefix":"10.1128","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0281-4895","authenticated-orcid":false,"given":"Mike Marvin","family":"Ruth","sequence":"first","affiliation":[{"name":"Radboud Center for Infectious Diseases, Department of Medical Microbiology, Radboud University Medical Center, Nijmegen, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3343-6823","authenticated-orcid":false,"given":"Lian J.","family":"Pennings","sequence":"additional","affiliation":[{"name":"Radboud Center for Infectious Diseases, Department of Medical Microbiology, Radboud University Medical Center, Nijmegen, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valerie A. 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