{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T09:16:39Z","timestamp":1784193399481,"version":"3.55.0"},"reference-count":22,"publisher":"American Society for Microbiology","issue":"6","license":[{"start":{"date-parts":[[2013,6,1]],"date-time":"2013-06-01T00:00:00Z","timestamp":1370044800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2013,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            Two homosexual men were colonized in the urethra with\n            <jats:named-content xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" content-type=\"genus-species\" xlink:type=\"simple\">Haemophilus parainfluenzae<\/jats:named-content>\n            nonsusceptible to ampicillin (MIC, 8 \u03bcg\/ml), amoxicillin-clavulanate (MIC, 4 \u03bcg\/ml), cefotaxime (MIC, 1.5 \u03bcg\/ml), cefepime (MIC, 3 \u03bcg\/ml), meropenem (MIC, 0.5 \u03bcg\/ml), cefuroxime, azithromycin, ciprofloxacin, tetracycline, and chloramphenicol (all MICs, \u226532 \u03bcg\/ml). Repetitive extragenic palindromic PCR (rep-PCR) showed that the strains were indistinguishable. The isolates had amino acid substitutions in PBP3, L4, GyrA, and ParC and possessed Mef(A), Tet(M), and CatS resistance mechanisms. This is the first report of extensively drug-resistant (XDR)\n            <jats:named-content xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" content-type=\"genus-species\" xlink:type=\"simple\">H. parainfluenzae<\/jats:named-content>\n            .\n          <\/jats:p>","DOI":"10.1128\/aac.00221-13","type":"journal-article","created":{"date-parts":[[2013,4,2]],"date-time":"2013-04-02T01:53:52Z","timestamp":1364867632000},"page":"2867-2869","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":35,"title":["Emergence of Extensively Drug-Resistant Haemophilus parainfluenzae in Switzerland"],"prefix":"10.1128","volume":"57","author":[{"given":"Regula","family":"Tinguely","sequence":"first","affiliation":[{"name":"Institute for Infectious Diseases, Faculty of Medicine, University of Bern, Bern, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salome N.","family":"Seiffert","sequence":"additional","affiliation":[{"name":"Institute for Infectious Diseases, Faculty of Medicine, University of Bern, Bern, Switzerland"},{"name":"Institute of Veterinary Bacteriology, Vetsuisse Faculty, University of Bern, Bern, Switzerland"},{"name":"Graduate School for Cellular and Biomedical Sciences, University of Bern, Bern, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hansjakob","family":"Furrer","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Bern University Hospital and University of Bern, Bern, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent","family":"Perreten","sequence":"additional","affiliation":[{"name":"Institute of Veterinary Bacteriology, Vetsuisse Faculty, University of Bern, Bern, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Droz","sequence":"additional","affiliation":[{"name":"Institute for Infectious Diseases, Faculty of Medicine, University of Bern, Bern, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Endimiani","sequence":"additional","affiliation":[{"name":"Institute for Infectious Diseases, Faculty of Medicine, University of Bern, Bern, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2011.03570.x"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00040-06"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1089\/mdr.2012.0060"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dks525"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkm523"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1155\/2010\/525919"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkq473"},{"key":"e_1_3_2_9_2","unstructured":"EUCAST. 2013. 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Rapid detection of Haemophilus influenzae and Haemophilus parainfluenzae in nasopharyngeal swabs by multiplex PCR. Biomed. Environ. Sci. 25:367\u2013371.","journal-title":"Biomed. Environ. Sci"},{"key":"e_1_3_2_19_2","article-title":"Haemophilus parainfluenzae urethritis among homosexual men","author":"Hsu MS","year":"2013","unstructured":"HsuMS WuMY LinTH LiaoCH. 2013. Haemophilus parainfluenzae urethritis among homosexual men. J. Microbiol. Immunol. Infect. doi:10.1016\/j.jmii.2012.11.007.","journal-title":"J. Microbiol. Immunol. Infect"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.diagmicrobio.2009.02.015"},{"key":"e_1_3_2_21_2","first-page":"213","article-title":"Haemophilus parainfluenzae meningitis in an adult associated with acute otitis media","volume":"32","author":"Cardines R","year":"2009","unstructured":"CardinesR GiufreM Ciofi degli AttiML AccogliM MastrantonioP CerquettiM. 2009. Haemophilus parainfluenzae meningitis in an adult associated with acute otitis media. 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