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This study tested the standard medium RPMI\n                      <jats:sub>1640<\/jats:sub>\n                      and healthy lung and sinus media against\n                      <jats:italic toggle=\"yes\">Aspergillus<\/jats:italic>\n                      ,\n                      <jats:italic toggle=\"yes\">Mucor<\/jats:italic>\n                      , and\n                      <jats:italic toggle=\"yes\">Candida<\/jats:italic>\n                      species.\n                      <jats:italic toggle=\"yes\">Candida<\/jats:italic>\n                      showed greater variability in minimum inhibitory concentrations (MICs) compared with molds, with higher MICs in respiratory tract-mimicking media than in RPMI\n                      <jats:sub>1640<\/jats:sub>\n                      .\n                      <jats:italic toggle=\"yes\">Aspergillus terreus<\/jats:italic>\n                      was the most affected mold, showing higher MICs for certain antifungals in these media.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1128\/aac.00225-25","type":"journal-article","created":{"date-parts":[[2025,6,17]],"date-time":"2025-06-17T05:49:46Z","timestamp":1750139386000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":2,"title":["The impact of respiratory tract mimicking media on antifungal susceptibility testing"],"prefix":"10.1128","volume":"69","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7518-7795","authenticated-orcid":true,"given":"Roya","family":"Vahedi-Shahandashti","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/054pv6659","id-type":"ROR","asserted-by":"publisher"}],"name":"Institute of Hygiene and Medical Microbiology, Medical University of Innsbruck","place":["Innsbruck, Austria"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabella","family":"Hofer","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/054pv6659","id-type":"ROR","asserted-by":"publisher"}],"name":"Institute of Hygiene and Medical Microbiology, Medical University of Innsbruck","place":["Innsbruck, Austria"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hollie","family":"Leighton","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/04xs57h96","id-type":"ROR","asserted-by":"publisher"}],"name":"Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool","place":["Liverpool, United Kingdom"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joanne L","family":"Fothergill","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/04xs57h96","id-type":"ROR","asserted-by":"publisher"}],"name":"Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool","place":["Liverpool, United Kingdom"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel R","family":"Neill","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03h2bxq36","id-type":"ROR","asserted-by":"publisher"}],"name":"Division of Molecular Microbiology, School of Life Sciences, University of Dundee","place":["Dundee, United Kingdom"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2946-7785","authenticated-orcid":true,"given":"Cornelia","family":"Lass-Fl\u00f6rl","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/054pv6659","id-type":"ROR","asserted-by":"publisher"}],"name":"Institute of Hygiene and Medical Microbiology, Medical University of Innsbruck","place":["Innsbruck, Austria"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.3004404"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1080\/13693780600826715"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkx444"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1136\/ejhpharm-2017-001467"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00069-19"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmi.2018.01.002"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/civ933"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.14.4.643-658.2001"},{"key":"e_1_3_3_10_2","first-page":"107","article-title":"Effect of test medium on in vitro susceptibility testing results for Aspergillus fumigatus","volume":"17","author":"Chandrasekar PH","year":"2000","unstructured":"Chandrasekar PH, Abraham OC, Manavathu EK, Nune U, Kanuri K. 2000. Effect of test medium on in vitro susceptibility testing results for Aspergillus fumigatus. Rev Iberoam Micol 17:107\u2013110.","journal-title":"Rev Iberoam Micol"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.3390\/jof9100973"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1128\/aac.02274-21"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.12688\/f1000research.125074.2"},{"key":"e_1_3_3_14_2","unstructured":"Arendrup MC Meletiadis J Mouton JW Lagrou K Hamal P Guinea J. 2020. Eucast definitive document E.def 9.3.2 23"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mpmed.2016.03.015"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/4737321"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12070-012-0500-2"},{"key":"e_1_3_3_18_2","unstructured":"Cook S Pharm Jc. 2011. 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