{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T18:30:06Z","timestamp":1787941806032,"version":"build-2784847793"},"reference-count":23,"publisher":"American Society for Microbiology","issue":"4","license":[{"start":{"date-parts":[[2015,4,1]],"date-time":"2015-04-01T00:00:00Z","timestamp":1427846400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2015,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            The macrolide resistance gene\n            <jats:italic>erm<\/jats:italic>\n            (T) was identified for the first time in a porcine\n            <jats:named-content xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" content-type=\"genus-species\" xlink:type=\"simple\">Erysipelothrix rhusiopathiae<\/jats:named-content>\n            isolate from swine in China. The novel 3,749-bp small plasmid pER29, which carries\n            <jats:italic>erm<\/jats:italic>\n            (T), had a G+C content of 31% and four distinct open reading frames. The presence of pER29 increased by at least 128-fold the MICs of clindamycin and erythromycin for\n            <jats:named-content xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" content-type=\"genus-species\" xlink:type=\"simple\">E. rhusiopathiae<\/jats:named-content>\n            . The fitness cost of pER29 could be responsible for the low frequency of\n            <jats:italic>erm<\/jats:italic>\n            (T) in\n            <jats:named-content xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" content-type=\"genus-species\" xlink:type=\"simple\">E. rhusiopathiae<\/jats:named-content>\n            .\n          <\/jats:p>","DOI":"10.1128\/aac.00228-15","type":"journal-article","created":{"date-parts":[[2015,2,10]],"date-time":"2015-02-10T02:47:33Z","timestamp":1423536453000},"page":"2462-2465","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":21,"title":["First Report of Macrolide Resistance Gene\n            <i>erm<\/i>\n            (T) Harbored by a Novel Small Plasmid from Erysipelothrix rhusiopathiae"],"prefix":"10.1128","volume":"59","author":[{"given":"Chang-Wen","family":"Xu","sequence":"first","affiliation":[{"name":"College of Life Sciences, Sichuan University; Animal Disease Prevention and Food Safety Key Laboratory of Sichuan Province; Key Laboratory of Bio-resources and Eco-environment, Ministry of Education; and 985 Project Science Innovative Platform for Resource and Environment Protection of Southwestern China, Chengdu, Sichuan, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"An-Yun","family":"Zhang","sequence":"additional","affiliation":[{"name":"College of Life Sciences, Sichuan University; Animal Disease Prevention and Food Safety Key Laboratory of Sichuan Province; Key Laboratory of Bio-resources and Eco-environment, Ministry of Education; and 985 Project Science Innovative Platform for Resource and Environment Protection of Southwestern China, Chengdu, Sichuan, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun-Mei","family":"Yang","sequence":"additional","affiliation":[{"name":"College of Life Sciences, Sichuan University; Animal Disease Prevention and Food Safety Key Laboratory of Sichuan Province; Key Laboratory of Bio-resources and Eco-environment, Ministry of Education; and 985 Project Science Innovative Platform for Resource and Environment Protection of Southwestern China, Chengdu, Sichuan, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun","family":"Pan","sequence":"additional","affiliation":[{"name":"College of Life Sciences, Sichuan University; Animal Disease Prevention and Food Safety Key Laboratory of Sichuan Province; Key Laboratory of Bio-resources and Eco-environment, Ministry of Education; and 985 Project Science Innovative Platform for Resource and Environment Protection of Southwestern China, Chengdu, Sichuan, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhong-Bin","family":"Guan","sequence":"additional","affiliation":[{"name":"College of Life Sciences, Sichuan University; Animal Disease Prevention and Food Safety Key Laboratory of Sichuan Province; Key Laboratory of Bio-resources and Eco-environment, Ministry of Education; and 985 Project Science Innovative Platform for Resource and Environment Protection of Southwestern China, Chengdu, Sichuan, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chang-Wei","family":"Lei","sequence":"additional","affiliation":[{"name":"College of Life Sciences, Sichuan University; Animal Disease Prevention and Food Safety Key Laboratory of Sichuan Province; Key Laboratory of Bio-resources and Eco-environment, Ministry of Education; and 985 Project Science Innovative Platform for Resource and Environment Protection of Southwestern China, Chengdu, Sichuan, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin-Yao","family":"Peng","sequence":"additional","affiliation":[{"name":"College of Life Sciences, Sichuan University; Animal Disease Prevention and Food Safety Key Laboratory of Sichuan Province; Key Laboratory of Bio-resources and Eco-environment, Ministry of Education; and 985 Project Science Innovative Platform for Resource and Environment Protection of Southwestern China, Chengdu, Sichuan, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qing-Zhou","family":"Li","sequence":"additional","affiliation":[{"name":"College of Life Sciences, Sichuan University; Animal Disease Prevention and Food Safety Key Laboratory of Sichuan Province; Key Laboratory of Bio-resources and Eco-environment, Ministry of Education; and 985 Project Science Innovative Platform for Resource and Environment Protection of Southwestern China, Chengdu, Sichuan, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong-Ning","family":"Wang","sequence":"additional","affiliation":[{"name":"College of Life Sciences, Sichuan University; Animal Disease Prevention and Food Safety Key Laboratory of Sichuan Province; Key Laboratory of Bio-resources and Eco-environment, Ministry of Education; and 985 Project Science Innovative Platform for Resource and Environment Protection of Southwestern China, Chengdu, Sichuan, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_3_2_2","first-page":"409","article-title":"Serological and pathogenic characterization of Erysipelothrix rhusiopathiae isolates from two human cases of endocarditis in Japan","volume":"34","author":"Harada K","year":"2011","unstructured":"Harada K, Amano K, Akimoto S, Yamamoto K, Yamamoto Y, Yanagihara K, Kohno S, Kishida N, Takahashi T. 2011. 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