{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:29:47Z","timestamp":1787016587614,"version":"build-2736575974"},"reference-count":34,"publisher":"American Society for Microbiology","issue":"6","license":[{"start":{"date-parts":[[2021,5,18]],"date-time":"2021-05-18T00:00:00Z","timestamp":1621296000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"DOI":"10.13039\/100000002","name":"HHS | National Institutes of Health","doi-asserted-by":"publisher","award":["Intramural funds"],"award-info":[{"award-number":["Intramural funds"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2021,5,18]]},"abstract":"<jats:p>\n                    <jats:italic>In vitro<\/jats:italic>\n                    antifungal susceptibility profiling of 32 clinical and environmental\n                    <jats:named-content content-type=\"genus-species\">Talaromyces marneffei<\/jats:named-content>\n                    isolates recovered from southern China was performed against olorofim and 7 other systemic antifungals, including amphotericin B, 5-flucytosine, posaconazole, voriconazole, caspofungin, and terbinafine, using CLSI methodology. In comparison, olorofim was the most active antifungal agent against both mold and yeast phases of all tested\n                    <jats:italic>Talaromyces marneffei<\/jats:italic>\n                    isolates, exhibiting an MIC range, MIC\n                    <jats:sub>50<\/jats:sub>\n                    , and MIC\n                    <jats:sub>90<\/jats:sub>\n                    of 0.0005 to 0.002\u2009\u03bcg\/ml, 0.0005\u2009\u03bcg\/ml, and 0.0005\u2009\u03bcg\/ml, respectively.\n                  <\/jats:p>","DOI":"10.1128\/aac.00256-21","type":"journal-article","created":{"date-parts":[[2021,3,23]],"date-time":"2021-03-23T09:46:06Z","timestamp":1616492766000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":35,"title":["Antifungal Susceptibility Profiles of Olorofim (Formerly F901318) and Currently Available Systemic Antifungals against Mold and Yeast Phases of\n                    <i>Talaromyces marneffei<\/i>"],"prefix":"10.1128","volume":"65","author":[{"given":"Jing","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Dermatology and Venerology, Sun Yat-sen Memorial Hospital of Sun Yat-sen University, Guangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongfang","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Dermatology Hospital of Southern Medical University, Guangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liyan","family":"Xi","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venerology, Sun Yat-sen Memorial Hospital of Sun Yat-sen University, Guangzhou, China"},{"name":"Department of Dermatology, Dermatology Hospital of Southern Medical University, Guangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun C.","family":"Chang","sequence":"additional","affiliation":[{"name":"Molecular Microbiology Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyung J.","family":"Kwon-Chung","sequence":"additional","affiliation":[{"name":"Molecular Microbiology Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6194-7447","authenticated-orcid":true,"given":"Seyedmojtaba","family":"Seyedmousavi","sequence":"additional","affiliation":[{"name":"Molecular Microbiology Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA"},{"name":"Microbiology Service, Department of 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