{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T19:49:09Z","timestamp":1760384949265},"reference-count":26,"publisher":"American Society for Microbiology","issue":"8","license":[{"start":{"date-parts":[[2009,8,1]],"date-time":"2009-08-01T00:00:00Z","timestamp":1249084800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2009,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            We evaluated the efficacies of posaconazole and voriconazole in comparison with that of amphotericin B in a systemic murine infection by\n            <jats:italic>Candida krusei.<\/jats:italic>\n            Posaconazole at 50 mg\/kg\/day and voriconazole at 40 and 60 mg\/kg\/day prolonged survival and reduced the fungal tissue burden in the kidneys of mice similarly to amphotericin B at 1.5 mg\/kg\/day and liposomal amphotericin B at 10 mg\/kg\/day. None of the treatments tested completely resolved the infection.\n          <\/jats:p>","DOI":"10.1128\/aac.00293-09","type":"journal-article","created":{"date-parts":[[2009,5,27]],"date-time":"2009-05-27T02:09:08Z","timestamp":1243390148000},"page":"3585-3588","update-policy":"http:\/\/dx.doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":8,"title":["Efficacy of Triazoles in a Murine Disseminated Infection by\n            <i>Candida krusei<\/i>"],"prefix":"10.1128","volume":"53","author":[{"given":"Marc\u0327al","family":"Marine\u0301","sequence":"first","affiliation":[{"name":"Unitat de Microbiologia, Facultat de Medicina i Cie\u0300ncies de la Salut, IISPV, Universitat Rovira i Virgili, Reus, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F. Javier","family":"Pastor","sequence":"additional","affiliation":[{"name":"Unitat de Microbiologia, Facultat de Medicina i Cie\u0300ncies de la Salut, IISPV, Universitat Rovira i Virgili, Reus, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carolina","family":"Serena","sequence":"additional","affiliation":[{"name":"Unitat de Microbiologia, Facultat de Medicina i Cie\u0300ncies de la Salut, IISPV, Universitat Rovira i Virgili, Reus, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Josep","family":"Guarro","sequence":"additional","affiliation":[{"name":"Unitat de Microbiologia, Facultat de Medicina i Cie\u0300ncies de la Salut, IISPV, Universitat Rovira i Virgili, Reus, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","unstructured":"Fungicidal activity of voriconazole against Candida krusei by time-kill curves. 2002"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/IPC.0b013e318059b94b"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)67490-9"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.43.3.589"},{"key":"e_1_3_2_6_2","first-page":"161","volume":"63","year":"2009","unstructured":"Majithiya, J., A. Sharp, A. Parmar, D. W. Denning, and P. A. Warn. 2009. Efficacy of isavuconazole, voriconazole and fluconazole in temporarily neutropenic murine models of disseminated Candida tropicalis and Candida krusei. J. Antimicrob. Chemother.63:161-166.","journal-title":"J. Antimicrob. 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O. S\u00e1nchez-Vargas, M. Villar-Vidal, E. Eraso, M. Alkorta, and J. L. Hern\u00e1ndez-Almaraz. 2008. Activities of fluconazole and voriconazole against bloodstream isolates of Candida glabrata and Candida krusei: a 14-year study in a Spanish tertiary medical centre. Int. J. Antimicrob. Agents31:266-271.","journal-title":"Int. J. Antimicrob. Agents"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01477-08"},{"key":"e_1_3_2_20_2","first-page":"361","volume":"63","year":"2009","unstructured":"Rodr\u00edguez, M. M., F. J. Pastor, C. Serena, and J. Guarro. 2009. Posaconazole efficacy in a murine disseminated infection caused by Paecilomyces lilacinus. J. Antimicrob. Chemother.63:361-364.","journal-title":"J. Antimicrob. 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