{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T19:50:25Z","timestamp":1760385025565},"reference-count":19,"publisher":"American Society for Microbiology","issue":"6","license":[{"start":{"date-parts":[[2010,6,1]],"date-time":"2010-06-01T00:00:00Z","timestamp":1275350400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2010,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            The activity of telavancin and comparators was assessed against a contemporary (2007 and 2008) global collection of 10,000 isolates of\n            <jats:italic>Staphylococcus aureus<\/jats:italic>\n            . Telavancin was very active against methicillin-susceptible and -resistant\n            <jats:italic>S<\/jats:italic>\n            .\n            <jats:italic>aureus<\/jats:italic>\n            (MSSA and MRSA, respectively; MIC\n            <jats:sub>50\/90<\/jats:sub>\n            for both, 0.12\/0.25 \u03bcg\/ml; 100.0% susceptible). This agent was 2-, 4-, and 8-fold more potent than daptomycin (MIC\n            <jats:sub>90<\/jats:sub>\n            , 0.5 \u03bcg\/ml), vancomycin or quinupristin-dalfopristin (MIC\n            <jats:sub>90<\/jats:sub>\n            , 1 \u03bcg\/ml), and linezolid (MIC\n            <jats:sub>90<\/jats:sub>\n            , 2 \u03bcg\/ml) against MRSA, respectively. These data show a potent activity of telavancin tested against a current global collection of\n            <jats:italic>S<\/jats:italic>\n            .\n            <jats:italic>aureus<\/jats:italic>\n            .\n          <\/jats:p>","DOI":"10.1128\/aac.00301-10","type":"journal-article","created":{"date-parts":[[2010,4,13]],"date-time":"2010-04-13T03:45:08Z","timestamp":1271130308000},"page":"2704-2706","update-policy":"http:\/\/dx.doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":26,"title":["<i>In Vitro<\/i>\n            Activity of Telavancin against a Contemporary Worldwide Collection of\n            <i>Staphylococcus aureus<\/i>\n            Isolates"],"prefix":"10.1128","volume":"54","author":[{"given":"Rodrigo E.","family":"Mendes","sequence":"first","affiliation":[{"name":"JMI Laboratories, North Liberty, Iowa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gary J.","family":"Moet","sequence":"additional","affiliation":[{"name":"JMI Laboratories, North Liberty, Iowa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mike J.","family":"Janechek","sequence":"additional","affiliation":[{"name":"JMI Laboratories, North Liberty, Iowa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ronald N.","family":"Jones","sequence":"additional","affiliation":[{"name":"JMI Laboratories, North Liberty, Iowa"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","unstructured":"VIBATIV package insert 2010"},{"key":"e_1_3_2_3_2","unstructured":"M07-A7 Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically; approved standard\u2014seventh edition 2006"},{"key":"e_1_3_2_4_2","unstructured":"M100-S19. 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