{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T08:59:06Z","timestamp":1771577946712,"version":"3.50.1"},"reference-count":28,"publisher":"American Society for Microbiology","issue":"6","license":[{"start":{"date-parts":[[2015,6,1]],"date-time":"2015-06-01T00:00:00Z","timestamp":1433116800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2015,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            Genome alignment of a macrolide, lincosamide, and streptogramin B (MLS\n            <jats:sub>B<\/jats:sub>\n            )-resistant\n            <jats:named-content xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" content-type=\"genus-species\" xlink:type=\"simple\">Staphylococcus fleurettii<\/jats:named-content>\n            strain with an MLS\n            <jats:sub>B<\/jats:sub>\n            -susceptible\n            <jats:named-content xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" content-type=\"genus-species\" xlink:type=\"simple\">S. fleurettii<\/jats:named-content>\n            strain revealed a novel 11,513-bp genomic island carrying the new erythromycin resistance methylase gene\n            <jats:italic>erm<\/jats:italic>\n            (45). This gene was shown to confer inducible MLS\n            <jats:sub>B<\/jats:sub>\n            resistance when cloned into\n            <jats:named-content xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" content-type=\"genus-species\" xlink:type=\"simple\">Staphylococcus aureus<\/jats:named-content>\n            . The\n            <jats:italic>erm<\/jats:italic>\n            (45)-containing island was integrated into the housekeeping gene\n            <jats:italic>guaA<\/jats:italic>\n            in\n            <jats:named-content xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" content-type=\"genus-species\" xlink:type=\"simple\">S. fleurettii<\/jats:named-content>\n            and was able to form a circular intermediate but was not transmissible to\n            <jats:named-content xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" content-type=\"genus-species\" xlink:type=\"simple\">S. aureus<\/jats:named-content>\n            .\n          <\/jats:p>","DOI":"10.1128\/aac.00369-15","type":"journal-article","created":{"date-parts":[[2015,3,17]],"date-time":"2015-03-17T02:56:01Z","timestamp":1426560961000},"page":"3578-3581","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":22,"title":["The New Macrolide-Lincosamide-Streptogramin B Resistance Gene\n            <i>erm<\/i>\n            (45) Is Located within a Genomic Island in Staphylococcus fleurettii"],"prefix":"10.1128","volume":"59","author":[{"given":"Juliette R. 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