{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T09:46:34Z","timestamp":1790934394380,"version":"4.1.0"},"reference-count":45,"publisher":"American Society for Microbiology","issue":"10","license":[{"start":{"date-parts":[[2021,9,17]],"date-time":"2021-09-17T00:00:00Z","timestamp":1631836800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/doi.org\/10.1128\/AuthorWarrantyLicense.v1"},{"start":{"date-parts":[[2021,9,17]],"date-time":"2021-09-17T00:00:00Z","timestamp":1631836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"DOI":"10.13039\/100000002","name":"HHS | National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2021,9,17]]},"abstract":"<jats:p>\n                    Clinically relevant members of the\n                    <jats:italic>Scedosporium<\/jats:italic>\n                    \/\n                    <jats:italic>Pseudallescheria<\/jats:italic>\n                    species complex and\n                    <jats:named-content content-type=\"genus-species\">Lomentospora prolificans<\/jats:named-content>\n                    are generally resistant against currently available systemic antifungal agents\n                    <jats:italic>in vitro<\/jats:italic>\n                    , and infection due to these species is difficult to treat. We studied the\n                    <jats:italic>in vivo<\/jats:italic>\n                    efficacy of a new fungicidal agent, olorofim (formerly F901318), against scedosporiosis and lomentosporiosis in neutropenic animals.\n                  <\/jats:p>","DOI":"10.1128\/aac.00434-21","type":"journal-article","created":{"date-parts":[[2021,7,12]],"date-time":"2021-07-12T17:01:25Z","timestamp":1626109285000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":43,"title":["<i>In Vivo<\/i>\n                    Efficacy of Olorofim against Systemic Scedosporiosis and Lomentosporiosis"],"prefix":"10.1128","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6194-7447","authenticated-orcid":true,"given":"S.","family":"Seyedmousavi","sequence":"first","affiliation":[{"name":"Microbiology Service, Department of Laboratory Medicine, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA"},{"name":"Molecular Microbiology Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y. 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