{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T16:02:03Z","timestamp":1761580923528},"reference-count":14,"publisher":"American Society for Microbiology","issue":"1","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2012,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            We investigated the utility of radioimmunotherapy (RIT) in early and established cryptococcal infection in immunocompetent mice. RIT with\n            <jats:sup>213<\/jats:sup>\n            Bi-18B7 antibody completely eliminated fungus from mouse lungs and brains for early infection, while\n            <jats:sup>188<\/jats:sup>\n            Re-18B7 significantly reduced CFU in the lungs or both lungs and brains during early and established infection, respectively. The results point to the independence of RIT of the immune status of the host, which is encouraging for translation of this strategy into the clinic.\n          <\/jats:p>","DOI":"10.1128\/aac.00473-11","type":"journal-article","created":{"date-parts":[[2011,10,18]],"date-time":"2011-10-18T05:22:42Z","timestamp":1318915362000},"page":"552-554","update-policy":"http:\/\/dx.doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":13,"title":["Treatment of Early and Established Cryptococcus neoformans Infection with Radiolabeled Antibodies in Immunocompetent Mice"],"prefix":"10.1128","volume":"56","author":[{"given":"Zewei","family":"Jiang","sequence":"first","affiliation":[{"name":"Departments of Nuclear Medicine, Albert Einstein College of Medicine, Bronx, New York, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruth A.","family":"Bryan","sequence":"additional","affiliation":[{"name":"Departments of Nuclear Medicine, Albert Einstein College of Medicine, Bronx, New York, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alfred","family":"Morgenstern","sequence":"additional","affiliation":[{"name":"European Commission, Joint Research Centre, Institute for Transuranium Elements, Karlsruhe, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frank","family":"Bruchertseifer","sequence":"additional","affiliation":[{"name":"European Commission, Joint Research Centre, Institute for Transuranium Elements, Karlsruhe, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arturo","family":"Casadevall","sequence":"additional","affiliation":[{"name":"Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, USA"},{"name":"Medicine, Albert Einstein College of Medicine, Bronx, New York, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ekaterina","family":"Dadachova","sequence":"additional","affiliation":[{"name":"Departments of Nuclear Medicine, Albert Einstein College of Medicine, Bronx, New York, USA"},{"name":"Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01245-07"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01334-08"},{"key":"e_1_3_2_4_2","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1086\/654813","article-title":"Radioimmunotherapy is more effective than antifungal treatment in experimental cryptococcal infection","volume":"202","author":"Bryan RA","year":"2010","unstructured":"BryanRA. 2010. Radioimmunotherapy is more effective than antifungal treatment in experimental cryptococcal infection. J. Infect. Dis. 202:633\u2013637.","journal-title":"J. Infect. Dis"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.42.4.899"},{"key":"e_1_3_2_6_2","doi-asserted-by":"crossref","first-page":"1427","DOI":"10.1086\/503369","article-title":"Interaction of radiolabeled antibodies with fungal cells and components of the immune system in vitro and during radioimmunotherapy for experimental fungal infection","volume":"193","author":"Dadachova E","year":"2006","unstructured":"DadachovaE. 2006. Interaction of radiolabeled antibodies with fungal cells and components of the immune system in vitro and during radioimmunotherapy for experimental fungal infection. J. Infect. Dis. 193:1427\u20131436.","journal-title":"J. Infect. Dis"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.48.3.1004-1006.2004"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.semnuclmed.2008.10.007"},{"key":"e_1_3_2_9_2","doi-asserted-by":"crossref","first-page":"10942","DOI":"10.1073\/pnas.1731272100","article-title":"Ionizing radiation delivered by specific antibody is therapeutic against a fungal infection","volume":"100","author":"Dadachova E","year":"2003","unstructured":"DadachovaE NakouziA BryanRA CasadevallA. 2003. Ionizing radiation delivered by specific antibody is therapeutic against a fungal infection. Proc. Natl. Acad. Sci. U. S. A. 100:10942\u201310947.","journal-title":"Proc. Natl. Acad. Sci. U. S. A"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0b013e328322ffac"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.29.2.494-499.1980"},{"key":"e_1_3_2_12_2","doi-asserted-by":"crossref","first-page":"3410","DOI":"10.1128\/IAI.69.5.3410-3412.2001","article-title":"Passive immunization with melanin-binding monoclonal antibodies prolongs survival of mice with lethal Cryptococcus neoformans infection","volume":"69","author":"Rosas AL","year":"2001","unstructured":"RosasAL NosanchukJD CasadevallA. 2001. Passive immunization with melanin-binding monoclonal antibodies prolongs survival of mice with lethal Cryptococcus neoformans infection. Infect. Immun. 69:3410\u20133412.","journal-title":"Infect. Immun"},{"key":"e_1_3_2_13_2","first-page":"115S","article-title":"Perspectives on cancer therapy with radio-labeled monoclonal antibodies","volume":"46","author":"Sharkey RM","year":"2005","unstructured":"SharkeyRM GoldenbergDM. 2005. Perspectives on cancer therapy with radio-labeled monoclonal antibodies. J. Nucl. Med. 46(Suppl. 1):115S\u2013127S.","journal-title":"J. Nucl. Med"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI41963"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.94.6.2483"}],"container-title":["Antimicrobial Agents and Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.00473-11","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.00473-11","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,21]],"date-time":"2022-02-21T22:28:58Z","timestamp":1645482538000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/AAC.00473-11"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,1]]},"references-count":14,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,1]]}},"alternative-id":["10.1128\/AAC.00473-11"],"URL":"https:\/\/doi.org\/10.1128\/aac.00473-11","relation":{},"ISSN":["0066-4804","1098-6596"],"issn-type":[{"value":"0066-4804","type":"print"},{"value":"1098-6596","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,1]]},"assertion":[{"value":"2011-04-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2011-10-07","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2012-12-26","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}