{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T19:03:55Z","timestamp":1791313435841,"version":"4.3.1"},"reference-count":25,"publisher":"American Society for Microbiology","issue":"9","license":[{"start":{"date-parts":[[2007,9,1]],"date-time":"2007-09-01T00:00:00Z","timestamp":1188604800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2007,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            We analyzed the emergence of daptomycin nonsusceptibility in a patient with persistent vancomycin-intermediate\n            <jats:italic>Staphylococcus aureus<\/jats:italic>\n            (VISA) bacteremia. The daptomycin-nonsusceptible VISA's cell wall demonstrated a reduction in muramic acid\n            <jats:italic>O<\/jats:italic>\n            -acetylation, a phenotypic parameter not previously reported for VISA; some isolates also contained a single point mutation in the\n            <jats:italic>mprF<\/jats:italic>\n            gene.\n          <\/jats:p>","DOI":"10.1128\/aac.00559-07","type":"journal-article","created":{"date-parts":[[2007,7,10]],"date-time":"2007-07-10T00:43:33Z","timestamp":1184028213000},"page":"3445-3448","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":109,"title":["Characterization of a Daptomycin-Nonsusceptible Vancomycin-Intermediate\n            <i>Staphylococcus aureus<\/i>\n            Strain in a Patient with Endocarditis"],"prefix":"10.1128","volume":"51","author":[{"given":"Kathleen","family":"Julian","sequence":"first","affiliation":[{"name":"Pennsylvania State University Milton S. 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