{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T23:02:13Z","timestamp":1791414133358,"version":"4.3.3"},"reference-count":10,"publisher":"American Society for Microbiology","issue":"9","license":[{"start":{"date-parts":[[2006,9,1]],"date-time":"2006-09-01T00:00:00Z","timestamp":1157068800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2006,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            The in vitro activities of DA-7157, a novel oxazolidinone, against clinical isolates of\n            <jats:italic>Nocardia brasiliensis<\/jats:italic>\n            and\n            <jats:italic>Mycobacterium tuberculosis<\/jats:italic>\n            were determined. Equal MIC\n            <jats:sub>50<\/jats:sub>\n            s and MIC\n            <jats:sub>90<\/jats:sub>\n            s (0.25 and 0.5 \u03bcg\/ml, respectively) were found for susceptible and multidrug-resistant isolates of\n            <jats:italic>M. tuberculosis<\/jats:italic>\n            . The\n            <jats:italic>N. brasiliensis<\/jats:italic>\n            isolates showed an MIC\n            <jats:sub>90<\/jats:sub>\n            of 1 \u03bcg\/ml and an MIC\n            <jats:sub>50<\/jats:sub>\n            of 1 \u03bcg\/ml. The DA-7157 prodrug, DA-7218, exhibited similar MICs for\n            <jats:italic>M. tuberculosis<\/jats:italic>\n            but fivefold-higher MICs for\n            <jats:italic>N. brasiliensis<\/jats:italic>\n            .\n          <\/jats:p>","DOI":"10.1128\/aac.00571-06","type":"journal-article","created":{"date-parts":[[2006,8,28]],"date-time":"2006-08-28T18:10:56Z","timestamp":1156788656000},"page":"3170-3172","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":68,"title":["In Vitro Activities of DA-7157 and DA-7218 against\n            <i>Mycobacterium tuberculosis<\/i>\n            and\n            <i>Nocardia brasiliensis<\/i>"],"prefix":"10.1128","volume":"50","author":[{"given":"Lucio","family":"Vera-Cabrera","sequence":"first","affiliation":[{"name":"Servicio de Dermatologi\u0301a, Hospital Universitario Jose\u0301 E. Gonza\u0301lez, Monterrey, N.L., Me\u0301xico 64460"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva","family":"Gonzalez","sequence":"additional","affiliation":[{"name":"Servicio de Dermatologi\u0301a, Hospital Universitario Jose\u0301 E. Gonza\u0301lez, Monterrey, N.L., Me\u0301xico 64460"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adrian","family":"Rendon","sequence":"additional","affiliation":[{"name":"Servicio de Neumologi\u0301a, Hospital Universitario Jose\u0301 E. Gonza\u0301lez, Monterrey, N.L., Me\u0301xico 64460"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge","family":"Ocampo-Candiani","sequence":"additional","affiliation":[{"name":"Servicio de Dermatologi\u0301a, Hospital Universitario Jose\u0301 E. Gonza\u0301lez, Monterrey, N.L., Me\u0301xico 64460"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oliverio","family":"Welsh","sequence":"additional","affiliation":[{"name":"Servicio de Dermatologi\u0301a, Hospital Universitario Jose\u0301 E. Gonza\u0301lez, Monterrey, N.L., Me\u0301xico 64460"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victor M.","family":"Velazquez-Moreno","sequence":"additional","affiliation":[{"name":"Servicio de Dermatologi\u0301a, Hospital Universitario Jose\u0301 E. Gonza\u0301lez, Monterrey, N.L., Me\u0301xico 64460"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung","family":"Hak Choi","sequence":"additional","affiliation":[{"name":"Research Laboratory, Dong-A Pharmaceutical Co., Ltd., Yongin, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmen","family":"Molina-Torres","sequence":"additional","affiliation":[{"name":"Servicio de Dermatologi\u0301a, Hospital Universitario Jose\u0301 E. Gonza\u0301lez, Monterrey, N.L., Me\u0301xico 64460"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dki148"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.48.3.832-837.2004"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dki437"},{"key":"e_1_3_1_5_2","first-page":"477","volume":"128","year":"1992","unstructured":"L\u00f3pez-Mart\u00ednez, R., L. J. M\u00e9ndez-Tovar, P. Lavalle, O. Welsh, A. Saul, and E. Macotela-Ru\u00edz. 1992. Epidemiolog\u00eda del micetoma en M\u00e9xico: estudio de 2105 casos. Gac. Med. Mex.128:477-481.","journal-title":"Gac. Med. Mex."},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1086\/345907"},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.1517\/13543784.8.8.1195"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.48.3.1037-1039.2004"},{"key":"e_1_3_1_9_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.49.10.4351-4353.2005"},{"key":"e_1_3_1_10_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.48.2.602-604.2004"},{"key":"e_1_3_1_11_2","first-page":"1402","year":"1994","unstructured":"Welsh, O., M. C. Salinas, and M. A. Rodr\u00edguez. 1994. Mycetoma, p. 1402-1406. In P. D. Hoeprich, M. C. Jordan, and A. R. Ronald (ed.), Infectious diseases, 5th ed. J. B. Lippincott Company, Philadelphia, Pa.","journal-title":"Infectious diseases"}],"container-title":["Antimicrobial Agents and Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.00571-06","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.00571-06","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,21]],"date-time":"2022-02-21T19:14:39Z","timestamp":1645470879000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/AAC.00571-06"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,9]]},"references-count":10,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2006,9]]}},"alternative-id":["10.1128\/AAC.00571-06"],"URL":"https:\/\/doi.org\/10.1128\/aac.00571-06","relation":{},"ISSN":["0066-4804","1098-6596"],"issn-type":[{"value":"0066-4804","type":"print"},{"value":"1098-6596","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,9]]},"assertion":[{"value":"2006-05-09","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2006-06-20","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2006-09-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}