{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,2]],"date-time":"2025-08-02T05:09:46Z","timestamp":1754111386806,"version":"3.41.2"},"reference-count":28,"publisher":"American Society for Microbiology","issue":"7","license":[{"start":{"date-parts":[[2024,7,9]],"date-time":"2024-07-09T00:00:00Z","timestamp":1720483200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/doi.org\/10.1128\/ASMCopyrightv2"},{"start":{"date-parts":[[2024,7,9]],"date-time":"2024-07-09T00:00:00Z","timestamp":1720483200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2024,7,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:sec>\n            <jats:title\/>\n            <jats:p>\n              Individuals with compromised lung function and immunity are susceptible to developing chronic\n              <jats:italic>Mycobacterium abscessus<\/jats:italic>\n              infection. Current treatment recommendations typically involve using one \u03b2-lactam antibiotic in combination with non-\u03b2-lactam antibiotics. However, a recent case study (B. Becken, K. M. Dousa, J. L. Johnson, S. M. Holland, and R. A. Bonomo, Antimicrob Agents Chemother 68:e00319-24, 2024,\n              <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/doi.org\/10.1128\/aac.00319-24\" xlink:type=\"simple\">https:\/\/doi.org\/10.1128\/aac.00319-24<\/jats:ext-link>\n              ) demonstrated successful treatment of chronic\n              <jats:italic>M. abscessus<\/jats:italic>\n              lung disease in a child using two \u03b2-lactam antibiotics simultaneously. This commentary reviews the emerging evidence and outstanding questions regarding dual \u03b2-lactam therapy for\n              <jats:italic>M. abscessus<\/jats:italic>\n              infections.\n            <\/jats:p>\n          <\/jats:sec>","DOI":"10.1128\/aac.00585-24","type":"journal-article","created":{"date-parts":[[2024,6,5]],"date-time":"2024-06-05T17:12:33Z","timestamp":1717607553000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":2,"title":["Case Commentary: Dual \u03b2-lactam as part of regimen to treat\n            <i>Mycobacterium abscessus<\/i>\n            lung disease"],"prefix":"10.1128","volume":"68","author":[{"given":"Christopher K.","family":"Lippincott","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA"},{"name":"Center for Nontuberculous Mycobacteria and Bronchiectasis, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2214-0114","authenticated-orcid":false,"given":"Gyanu","family":"Lamichhane","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA"},{"name":"Center for Nontuberculous Mycobacteria and Bronchiectasis, School of Medicine, Johns Hopkins University, Baltimore, Maryland, 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