{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T09:46:10Z","timestamp":1790934370965,"version":"4.1.0"},"reference-count":10,"publisher":"American Society for Microbiology","issue":"11","license":[{"start":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T00:00:00Z","timestamp":1762300800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T00:00:00Z","timestamp":1762300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2025,11,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title\/>\n                    <jats:p>\n                      <jats:italic toggle=\"yes\">Lomentospora prolificans<\/jats:italic>\n                      is a filamentous mold that can cause infections in both immunocompromised and immunocompetent individuals. Infection can be either focal or disseminated, often acquired via inhalation or direct conidia inoculation (A. Konsoula, C. Tsioutis, I. Markaki, M. Papadakis, A.P. Agouridis, N. Spernovasilis. Microorganisms 10:1317, 2022,\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/doi.org\/10.3390\/microorganisms10071317\" xlink:type=\"simple\">https:\/\/doi.org\/10.3390\/microorganisms10071317<\/jats:ext-link>\n                      ). This pathogen is challenging to treat due to its high MICs to available antifungals. We present a case of an 8-year-old previously healthy female who developed\n                      <jats:italic toggle=\"yes\">L. prolificans<\/jats:italic>\n                      knee tendonitis and synovitis with patellar osteomyelitis after a flat patio stone laceration in Southern California, who ultimately was treated with the novel antifungal, olorofim.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1128\/aac.00602-25","type":"journal-article","created":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T14:41:38Z","timestamp":1756305698000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":4,"title":["Successful use of olorofim for the treatment of\n                    <i>Lomentospora prolificans<\/i>\n                    knee tendonitis, synovitis, and concomitant osteomyelitis in an immunocompetent child"],"prefix":"10.1128","volume":"69","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-9364-343X","authenticated-orcid":true,"given":"Mary","family":"Fortini","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03r0ha626","id-type":"ROR","asserted-by":"publisher"}],"name":"Department of Pediatrics, Infectious Diseases Section, University of Utah and Primary Children\u2019s Hospital","place":["Salt Lake City, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Trahern W.","family":"Jones","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03r0ha626","id-type":"ROR","asserted-by":"publisher"}],"name":"Department of Pediatrics, Infectious Diseases Section, University of Utah and Primary Children\u2019s Hospital","place":["Salt Lake City, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2230-3745","authenticated-orcid":true,"given":"Tristan R.","family":"Grams","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03r0ha626","id-type":"ROR","asserted-by":"publisher"}],"name":"Department of Pathology-Medical Microbiology, University of Utah","place":["Salt Lake City, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonia","family":"Mehra","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03r0ha626","id-type":"ROR","asserted-by":"publisher"}],"name":"Department of Pediatrics, Infectious Diseases Section, University of Utah and Primary Children\u2019s Hospital","place":["Salt Lake City, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(20)30784-2"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.01550-24"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms10071317"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1128\/spectrum.02789-22"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.3390\/jof6030122"},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00487-18"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01527-20"},{"key":"e_1_3_1_9_2","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.01157-17"},{"key":"e_1_3_1_10_2","doi-asserted-by":"publisher","DOI":"10.1128\/cmr.00074-23"},{"key":"e_1_3_1_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(25)00224-5"}],"container-title":["Antimicrobial Agents and Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/aac.00602-25","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/aac.00602-25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T23:06:47Z","timestamp":1785884807000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/aac.00602-25"}},"subtitle":[],"editor":[{"given":"Cesar A.","family":"Arias","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2025,11,5]]},"references-count":10,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2025,11,5]]}},"alternative-id":["10.1128\/aac.00602-25"],"URL":"https:\/\/doi.org\/10.1128\/aac.00602-25","relation":{},"ISSN":["0066-4804","1098-6596"],"issn-type":[{"value":"0066-4804","type":"print"},{"value":"1098-6596","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,5]]},"assertion":[{"value":"2025-04-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-10","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-08-27","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication 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