{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T21:34:28Z","timestamp":1776202468445,"version":"3.50.1"},"reference-count":22,"publisher":"American Society for Microbiology","issue":"9","license":[{"start":{"date-parts":[[2017,9,1]],"date-time":"2017-09-01T00:00:00Z","timestamp":1504224000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"DOI":"10.13039\/100000774","name":"DOD | Defense Threat Reduction Agency","doi-asserted-by":"publisher","award":["02-4-2C-013"],"award-info":[{"award-number":["02-4-2C-013"]}],"id":[{"id":"10.13039\/100000774","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2017,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            <jats:italic>In vitro<\/jats:italic>\n            susceptibilities for 47 antibiotics were determined in 30 genetic diverse strains of\n            <jats:named-content content-type=\"genus-species\">Francisella tularensis<\/jats:named-content>\n            by the broth microdilution method following Clinical and Laboratory Standards Institute (CLSI) methods. The\n            <jats:named-content content-type=\"genus-species\">F. tularensis<\/jats:named-content>\n            strains demonstrated susceptibility to aminoglycosides, fluoroquinolones, and tetracyclines. There was a distinct difference in macrolide susceptibilities between A and B type strains, as has been noted previously. The establishment and comparison of antibiotic susceptibilities of a diverse but specific set of\n            <jats:named-content content-type=\"genus-species\">F. tularensis<\/jats:named-content>\n            strains by standardized methods and the establishment of population ranges and MIC\n            <jats:sub>50\/90<\/jats:sub>\n            values provide reference information for assessing new antibiotic agents and a baseline to monitor any future emergence of resistance, whether natural or intentional.\n          <\/jats:p>","DOI":"10.1128\/aac.00612-17","type":"journal-article","created":{"date-parts":[[2017,7,4]],"date-time":"2017-07-04T00:40:52Z","timestamp":1499128852000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":23,"title":["<i>In Vitro<\/i>\n            Antibiotic Susceptibilities of Francisella tularensis Determined by Broth Microdilution following CLSI Methods"],"prefix":"10.1128","volume":"61","author":[{"given":"Henry S.","family":"Heine","sequence":"first","affiliation":[{"name":"Bacteriology Division, U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lynda","family":"Miller","sequence":"additional","affiliation":[{"name":"Bacteriology Division, U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephanie","family":"Halasohoris","sequence":"additional","affiliation":[{"name":"Bacteriology Division, U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bret K.","family":"Purcell","sequence":"additional","affiliation":[{"name":"Bacteriology Division, U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1196\/annals.1409.009"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.285.21.2736"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid1207.051504"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01964409"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1080\/00365540110080773"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.3109\/00365548.2012.751125"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkr338"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dks238"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.5578\/mb.4179"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dks399"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/46.2.287"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.rvsc.2003.12.002"},{"key":"e_1_3_2_14_2","first-page":"84","article-title":"Sensitivity to macrolide antibiotics and lincomycin in Francisella tularensis holarctica","volume":"24","author":"Kudelina RI","year":"1980","unstructured":"Kudelina RI OlsufievNG. 1980. 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