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Two analogs of this compound with greater in vitro potency were tested against lethal murine\n            <jats:italic>Coccidioides<\/jats:italic>\n            infection. Both improved the survival of mice over that of controls; one resulted in near-sterilization of infection.\n          <\/jats:p>","DOI":"10.1128\/aac.00670-06","type":"journal-article","created":{"date-parts":[[2006,9,27]],"date-time":"2006-09-27T17:13:29Z","timestamp":1159377209000},"page":"3467-3469","update-policy":"http:\/\/dx.doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":22,"title":["Efficacy of Ambruticin Analogs in a Murine Model of Coccidioidomycosis"],"prefix":"10.1128","volume":"50","author":[{"given":"Lisa F.","family":"Shubitz","sequence":"first","affiliation":[{"name":"Department of Veterinary Science and Microbiology"},{"name":"Valley Fever Center for Excellence"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John N.","family":"Galgiani","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Arizona"},{"name":"Valley Fever Center for Excellence"},{"name":"Southern Arizona Veterans Health Care Administration, Tucson, Arizona"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zong-Qiang","family":"Tian","sequence":"additional","affiliation":[{"name":"Kosan Biosciences, Inc., Hayward, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ziyang","family":"Zhong","sequence":"additional","affiliation":[{"name":"Kosan Biosciences, Inc., Hayward, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pieter","family":"Timmermans","sequence":"additional","affiliation":[{"name":"Kosan Biosciences, Inc., Hayward, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leonard","family":"Katz","sequence":"additional","affiliation":[{"name":"Kosan Biosciences, Inc., Hayward, California"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1517\/13543784.10.2.269"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.7164\/antibiotics.53.1182"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.73.2.202"},{"key":"e_1_3_2_5_2","unstructured":"National Committee for Clinical Laboratory Standards. 2002. 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