{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T04:30:25Z","timestamp":1788323425703,"version":"build-2803163510"},"reference-count":26,"publisher":"American Society for Microbiology","issue":"11","license":[{"start":{"date-parts":[[2011,11,1]],"date-time":"2011-11-01T00:00:00Z","timestamp":1320105600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2011,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>Infections due to caspofungin-resistant<jats:named-content xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" content-type=\"genus-species\" xlink:type=\"simple\">Candida<\/jats:named-content>isolates in patients exposed to caspofungin therapy are increasing. We report here a nested case-control study which aimed at identifying factors associated with bloodstream infections caused by<jats:named-content xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" content-type=\"genus-species\" xlink:type=\"simple\">Candida<\/jats:named-content>spp. having reduced susceptibility to caspofungin (CRSC) in adults suffering from hematological malignancies. In univariate and multivariate analyses, infections with CRSC were associated with caspofungin exposure in the previous 30 days (odds ratio [OR] = 5.25; 95% confidence interval [95% CI], 1.68\u201316.35) and with an age of \u226465 years (OR = 3.27; 95% CI, 1.26\u20138.50).<\/jats:p>","DOI":"10.1128\/aac.00690-11","type":"journal-article","created":{"date-parts":[[2011,8,23]],"date-time":"2011-08-23T03:06:23Z","timestamp":1314068783000},"page":"5358-5361","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":43,"title":["Prior Caspofungin Exposure in Patients with Hematological Malignancies Is a Risk Factor for Subsequent Fungemia Due to Decreased Susceptibility in Candida spp.: a Case-Control Study in Paris, France"],"prefix":"10.1128","volume":"55","author":[{"given":"Elodie","family":"Blanchard","sequence":"first","affiliation":[{"name":"INSERM U 657, Paris, France"},{"name":"Institut Pasteur, Pharmacoepidemiology and Infectious Diseases Unit, Paris, France"},{"name":"Universit\u00e9 Versailles Saint Quentin, Facult\u00e9 de M\u00e9decine Paris Ile de France Ouest, EA 4499, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivier","family":"Lortholary","sequence":"additional","affiliation":[{"name":"Institut Pasteur, Unit\u00e9 de Mycologie Mol\u00e9culaire, Centre National de R\u00e9f\u00e9rence Mycologie et Antifongiques, Paris, France"},{"name":"CNRS URA 3012, Paris, France"},{"name":"Universit\u00e9 Paris Descartes, Service des Maladies Infectieuses et Tropicales, Centre d'Infectiologie Necker-Pasteur, H\u00f4pital Necker-Enfants Malades, APHP, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karine","family":"Boukris-Sitbon","sequence":"additional","affiliation":[{"name":"Institut Pasteur, Unit\u00e9 de Mycologie Mol\u00e9culaire, Centre National de R\u00e9f\u00e9rence Mycologie et Antifongiques, Paris, France"},{"name":"CNRS URA 3012, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie","family":"Desnos-Ollivier","sequence":"additional","affiliation":[{"name":"Institut Pasteur, Unit\u00e9 de Mycologie Mol\u00e9culaire, Centre National de R\u00e9f\u00e9rence Mycologie et Antifongiques, Paris, France"},{"name":"CNRS URA 3012, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7oise","family":"Dromer","sequence":"additional","affiliation":[{"name":"Institut Pasteur, Unit\u00e9 de Mycologie Mol\u00e9culaire, Centre National de R\u00e9f\u00e9rence Mycologie et Antifongiques, Paris, France"},{"name":"CNRS URA 3012, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Didier","family":"Guillemot","sequence":"additional","affiliation":[{"name":"INSERM U 657, Paris, France"},{"name":"Institut Pasteur, Pharmacoepidemiology and Infectious Diseases Unit, Paris, France"},{"name":"Universit\u00e9 Versailles Saint Quentin, Facult\u00e9 de M\u00e9decine Paris Ile de France Ouest, EA 4499, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"the French Mycosis Study Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkm095"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-005-2571-y"},{"key":"e_1_3_2_4_2","volume-title":"Proceedings of the 20th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID)","author":"Dannaoui E.","year":"2010","unstructured":"DannaouiE.. 2010. 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