{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T03:11:07Z","timestamp":1791342667827,"version":"4.3.1"},"reference-count":10,"publisher":"American Society for Microbiology","issue":"10","license":[{"start":{"date-parts":[[2013,10,1]],"date-time":"2013-10-01T00:00:00Z","timestamp":1380585600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2013,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            We compared the fitness and lung pathogenicity of two isogenic clinical isolates of\n            <jats:named-content xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" content-type=\"genus-species\" xlink:type=\"simple\">Acinetobacter baumannii<\/jats:named-content>\n            , one resistant (ABCR) and the other susceptible (ABCS) to colistin.\n            <jats:italic>In vitro<\/jats:italic>\n            , ABCR exhibited slower growth kinetics than ABCS. In a rat model of pneumonia, ABCR was associated with less pronounced signs of infection (lung bacterial count, systemic dissemination, and lung damage) and a better outcome (ABCR and ABCS mortality rates, 20 and 50%, respectively [\n            <jats:italic>P<\/jats:italic>\n            = 0.03]).\n          <\/jats:p>","DOI":"10.1128\/aac.00700-13","type":"journal-article","created":{"date-parts":[[2013,7,9]],"date-time":"2013-07-09T02:42:23Z","timestamp":1373337743000},"page":"5120-5121","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":41,"title":["Impaired Virulence and Fitness of a Colistin-Resistant Clinical Isolate of Acinetobacter baumannii in a Rat Model of Pneumonia"],"prefix":"10.1128","volume":"57","author":[{"given":"Sami","family":"Hraiech","sequence":"first","affiliation":[{"name":"Aix-Marseille Universit\u00e9, URMITE, UM63, CNRS 7278, IRD 198, INSERM 1095, Marseille, France"},{"name":"APHM, CHU Nord, R\u00e9animation, Marseille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antoine","family":"Roch","sequence":"additional","affiliation":[{"name":"Aix-Marseille Universit\u00e9, URMITE, UM63, CNRS 7278, IRD 198, INSERM 1095, Marseille, France"},{"name":"APHM, CHU Nord, R\u00e9animation, Marseille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hubert","family":"Lepidi","sequence":"additional","affiliation":[{"name":"Aix-Marseille Universit\u00e9, URMITE, UM63, CNRS 7278, IRD 198, INSERM 1095, Marseille, France"},{"name":"APHM, CHU Timone, Service d'Anatomie Pathologique, Marseille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Th\u00e9r\u00e8se","family":"Atieh","sequence":"additional","affiliation":[{"name":"Aix-Marseille Universit\u00e9, URMITE, UM63, CNRS 7278, IRD 198, INSERM 1095, Marseille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gilles","family":"Audoly","sequence":"additional","affiliation":[{"name":"Aix-Marseille Universit\u00e9, URMITE, UM63, CNRS 7278, IRD 198, INSERM 1095, Marseille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Marc","family":"Rolain","sequence":"additional","affiliation":[{"name":"Aix-Marseille Universit\u00e9, URMITE, UM63, CNRS 7278, IRD 198, INSERM 1095, Marseille, France"},{"name":"APHM, CHU Timone, P\u00f4le Infectieux, Marseille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Didier","family":"Raoult","sequence":"additional","affiliation":[{"name":"Aix-Marseille Universit\u00e9, URMITE, UM63, CNRS 7278, IRD 198, INSERM 1095, Marseille, France"},{"name":"APHM, CHU Timone, P\u00f4le Infectieux, Marseille, 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