{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T22:49:17Z","timestamp":1790549357097,"version":"4.1.0"},"reference-count":23,"publisher":"American Society for Microbiology","issue":"8","license":[{"start":{"date-parts":[[2018,8,1]],"date-time":"2018-08-01T00:00:00Z","timestamp":1533081600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2018,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            A multidrug-resistant (MDR)\n            <jats:named-content content-type=\"genus-species\">Pseudomonas fulva<\/jats:named-content>\n            strain was isolated in 2006 from a urine sample. The isolate harbored the\n            <jats:italic>bla<\/jats:italic>\n            <jats:sub>IMP-1<\/jats:sub>\n            gene, which was located in a chromosomal Tn\n            <jats:italic>402<\/jats:italic>\n            -like class 3 integron as a gene cassette array of\n            <jats:italic>aacA31-fosE-bla<\/jats:italic>\n            <jats:sub>IMP-1<\/jats:sub>\n            . Two mutations in\n            <jats:italic>gyrA<\/jats:italic>\n            and one mutation in\n            <jats:italic>parC<\/jats:italic>\n            were detected in quinolone-resistance-determining regions (QRDRs). We report a full-length, novel,\n            <jats:italic>bla<\/jats:italic>\n            <jats:sub>IMP-1<\/jats:sub>\n            -carrying class 3 integron. This integron, together with mutations in QRDRs, could have influenced the MDR phenotype.\n          <\/jats:p>","DOI":"10.1128\/aac.00701-18","type":"journal-article","created":{"date-parts":[[2018,5,18]],"date-time":"2018-05-18T09:35:23Z","timestamp":1526636123000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":6,"title":["Molecular Analysis of a\n            <i>bla<\/i>\n            <sub>IMP-1<\/sub>\n            -Harboring Class 3 Integron in Multidrug-Resistant Pseudomonas fulva"],"prefix":"10.1128","volume":"62","author":[{"given":"Masaki","family":"Yamamoto","sequence":"first","affiliation":[{"name":"Department of Clinical Laboratory Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8595-8944","authenticated-orcid":false,"given":"Yasufumi","family":"Matsumura","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3299-333X","authenticated-orcid":false,"given":"Ryota","family":"Gomi","sequence":"additional","affiliation":[{"name":"Department of Environmental Engineering, Graduate School of Engineering, Kyoto University, Kyoto, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomonari","family":"Matsuda","sequence":"additional","affiliation":[{"name":"Research Center for Environmental Quality Management, Kyoto University, Shiga, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoshi","family":"Nakano","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miki","family":"Nagao","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michio","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoshi","family":"Ichiyama","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1099\/00221287-146-10-2385"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.03264-15"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(11)70056-1"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00588-16"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.184.11.3017-3026.2002"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkq166"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00937-15"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.39.7.1612"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/1469-0691.12186"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2016.06.018"},{"key":"e_1_3_3_12_2","volume-title":"CLSI M07-A10","author":"Clinical and Laboratory Standards Institute","year":"2015","unstructured":"Clinical and Laboratory Standards Institute. 2015. 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Clinical and Laboratory Standards Institute, Wayne, PA."},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.41.12.5407-5413.2003"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0085024"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1005595"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0906412106"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2164-9-75"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-2836(05)80360-2"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01310-13"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00933-16"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01388-12"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2009.05.013"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0042973"}],"container-title":["Antimicrobial Agents and Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.00701-18","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.00701-18","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,21]],"date-time":"2022-02-21T21:24:30Z","timestamp":1645478670000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/AAC.00701-18"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8]]},"references-count":23,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2018,8]]}},"alternative-id":["10.1128\/AAC.00701-18"],"URL":"https:\/\/doi.org\/10.1128\/aac.00701-18","relation":{},"ISSN":["0066-4804","1098-6596"],"issn-type":[{"value":"0066-4804","type":"print"},{"value":"1098-6596","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,8]]},"assertion":[{"value":"2018-04-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-05-15","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-07-27","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e00701-18"}}