{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T07:16:03Z","timestamp":1785568563050,"version":"3.56.0"},"reference-count":14,"publisher":"American Society for Microbiology","issue":"8","license":[{"start":{"date-parts":[[2019,8,1]],"date-time":"2019-08-01T00:00:00Z","timestamp":1564617600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"DOI":"10.13039\/100000002","name":"HHS | National Institutes of Health","doi-asserted-by":"publisher","award":["R01 AI057576"],"award-info":[{"award-number":["R01 AI057576"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2019,8]]},"abstract":"<jats:p>\n            In a previous study, mutants with enhanced ciprofloxacin resistance (Cip\n            <jats:sup>r<\/jats:sup>\n            ) were selected from\n            <jats:named-content content-type=\"genus-species\">Escherichia coli<\/jats:named-content>\n            J53\/pMG252 carrying\n            <jats:italic>qnrA1<\/jats:italic>\n            . Strain J53 Cip\n            <jats:sup>r<\/jats:sup>\n            8-2 showed an increase in the copy number and transcription level of\n            <jats:italic>qnrA1<\/jats:italic>\n            . We sequenced the plasmids on Illumina and MinION platforms.\n          <\/jats:p>","DOI":"10.1128\/aac.00718-19","type":"journal-article","created":{"date-parts":[[2019,5,30]],"date-time":"2019-05-30T11:20:38Z","timestamp":1559215238000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":8,"title":["Multiple Copies of\n            <i>qnrA1<\/i>\n            on an IncA\/C\n            <sub>2<\/sub>\n            Plasmid Explain Enhanced Quinolone Resistance in an Escherichia coli Mutant"],"prefix":"10.1128","volume":"63","author":[{"given":"Laura","family":"Vinu\u00e9","sequence":"first","affiliation":[{"name":"Massachusetts General Hospital, Boston, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamad R. 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Coexistence of plasmid-mediated quinolone resistance determinants and AmpC-beta-lactamases in Escherichia coli strains in Egypt. Cell Mol Biol (Noisy-le-grand) 61:29\u201335.","journal-title":"Cell Mol Biol (Noisy-le-grand)"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dks123"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00991-10"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.45.11.3189-3194.2001"}],"container-title":["Antimicrobial Agents and Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.00718-19","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.00718-19","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,21]],"date-time":"2022-02-21T21:29:30Z","timestamp":1645478970000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/AAC.00718-19"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8]]},"references-count":14,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2019,8]]}},"alternative-id":["10.1128\/AAC.00718-19"],"URL":"https:\/\/doi.org\/10.1128\/aac.00718-19","relation":{},"ISSN":["0066-4804","1098-6596"],"issn-type":[{"value":"0066-4804","type":"print"},{"value":"1098-6596","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,8]]},"assertion":[{"value":"2019-04-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-05-23","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-07-25","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e00718-19"}}