{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T04:17:55Z","timestamp":1772770675340,"version":"3.50.1"},"reference-count":20,"publisher":"American Society for Microbiology","issue":"11","license":[{"start":{"date-parts":[[2013,11,1]],"date-time":"2013-11-01T00:00:00Z","timestamp":1383264000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2013,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    This study aimed at investigating the\n                    <jats:italic>in vitro<\/jats:italic>\n                    activities of amoxicillin-clavulanate, doxycycline, ceftazidime, imipenem, and trimethoprim-sulfamethoxazole against\n                    <jats:named-content xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" content-type=\"genus-species\" xlink:type=\"simple\">Burkholderia pseudomallei<\/jats:named-content>\n                    in planktonic and biofilm forms, through broth microdilution and resazurin-based viability staining, respectively. In planktonic growth, the strains were susceptible to the drugs, while in biofilm growth, significantly higher antimicrobial concentrations were required, especially for ceftazidime and imipenem, surpassing the resistance breakpoints. These results highlight the importance of the routine evaluation of biofilm antimicrobial susceptibility.\n                  <\/jats:p>","DOI":"10.1128\/aac.00721-13","type":"journal-article","created":{"date-parts":[[2013,9,4]],"date-time":"2013-09-04T00:42:13Z","timestamp":1378255333000},"page":"5771-5773","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":14,"title":["<i>In Vitro<\/i>\n                    Activities of Amoxicillin-Clavulanate, Doxycycline, Ceftazidime, Imipenem, and Trimethoprim-Sulfamethoxazole against Biofilm of Brazilian Strains of Burkholderia pseudomallei"],"prefix":"10.1128","volume":"57","author":[{"given":"Tereza de Jesus Pinheiro Gomes","family":"Bandeira","sequence":"first","affiliation":[{"name":"Specialized Medical Mycology Center, Federal University of Cear\u00e1, Fortaleza, Cear\u00e1, Brazil"},{"name":"Postgraduate Program in Medical Microbiology, Federal University of Cear\u00e1, Fortaleza, Cear\u00e1, Brazil"},{"name":"LabPasteur\u2014DASA, Cear\u00e1, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Camila Alencar","family":"Moreira","sequence":"additional","affiliation":[{"name":"Postgraduate Program in Medical Microbiology, Federal University of Cear\u00e1, Fortaleza, Cear\u00e1, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raimunda S\u00e2mia Nogueira","family":"Brilhante","sequence":"additional","affiliation":[{"name":"Specialized Medical Mycology Center, Federal University of Cear\u00e1, Fortaleza, Cear\u00e1, Brazil"},{"name":"Postgraduate Program in Medical Sciences, Federal University of Cear\u00e1, Fortaleza, Cear\u00e1, Brazil"},{"name":"Postgraduate Program in Medical Microbiology, Federal University of Cear\u00e1, Fortaleza, Cear\u00e1, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D\u00e9bora de Souza Collares Maia","family":"Castelo-Branco","sequence":"additional","affiliation":[{"name":"Specialized Medical Mycology Center, Federal University of Cear\u00e1, Fortaleza, Cear\u00e1, Brazil"},{"name":"Postgraduate Program in Medical Microbiology, Federal University of Cear\u00e1, Fortaleza, Cear\u00e1, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manoel Paiva de Ara\u00fajo","family":"Neto","sequence":"additional","affiliation":[{"name":"Specialized Medical Mycology Center, Federal University of Cear\u00e1, Fortaleza, Cear\u00e1, Brazil"},{"name":"Postgraduate Program in Veterinary Science, State University of Cear\u00e1, Fortaleza, Cear\u00e1, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rossana de Aguiar","family":"Cordeiro","sequence":"additional","affiliation":[{"name":"Specialized Medical Mycology Center, Federal University of Cear\u00e1, Fortaleza, Cear\u00e1, Brazil"},{"name":"Postgraduate Program in Medical Sciences, Federal 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