{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T17:13:09Z","timestamp":1791825189198,"version":"4.3.4"},"reference-count":14,"publisher":"American Society for Microbiology","issue":"10","license":[{"start":{"date-parts":[[2022,10,18]],"date-time":"2022-10-18T00:00:00Z","timestamp":1666051200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/doi.org\/10.1128\/ASMCopyrightv2"},{"start":{"date-parts":[[2022,10,18]],"date-time":"2022-10-18T00:00:00Z","timestamp":1666051200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2022,10,18]]},"abstract":"<jats:p>\n            This is a retrospective single-center study of 24 patients who received ceftazidime-avibactam plus aztreonam (CZA\/ATM) for the treatment of VIM-type-producing Gram-negative bacillus (GNB) infections. The bacteria isolated were\n            <jats:italic>Enterobacterales<\/jats:italic>\n            in 22 patients and\n            <jats:named-content content-type=\"genus-species\">Pseudomonas aeruginosa<\/jats:named-content>\n            in 2. Sixteen out of 19 isolates showed synergistic activity. Two patients presented clinical failure at day 14, and the 30-day mortality was 17% (4\/24).\n          <\/jats:p>","DOI":"10.1128\/aac.00751-22","type":"journal-article","created":{"date-parts":[[2022,9,14]],"date-time":"2022-09-14T13:03:06Z","timestamp":1663160586000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":39,"title":["Ceftazidime-Avibactam plus Aztreonam for the Treatment of Infections by VIM-Type-Producing Gram-Negative Bacteria"],"prefix":"10.1128","volume":"66","author":[{"given":"Abiu","family":"Sempere","sequence":"first","affiliation":[{"name":"Infectious Diseases Department, Hospital Universitari Vall d'Hebron, Barcelona, Spain"},{"name":"Department of Medicine, Universitat Aut\u00f2noma de Barcelona, Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bel\u00e9n","family":"Vi\u00f1ado","sequence":"additional","affiliation":[{"name":"Microbiology Department, Hospital 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