{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T13:23:34Z","timestamp":1753881814476,"version":"3.41.2"},"reference-count":31,"publisher":"American Society for Microbiology","issue":"11","license":[{"start":{"date-parts":[[2024,11,6]],"date-time":"2024-11-06T00:00:00Z","timestamp":1730851200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/doi.org\/10.1128\/ASMCopyrightv2"},{"start":{"date-parts":[[2024,11,6]],"date-time":"2024-11-06T00:00:00Z","timestamp":1730851200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2024,11,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:sec>\n            <jats:title\/>\n            <jats:p>\n              Obesity affects over one-third of U.S. adults and complicates the treatment of methicillin-susceptible\n              <jats:italic>Staphylococcus aureus<\/jats:italic>\n              (MSSA) bloodstream infections (BSI). A study at the University of Florida Health Centers compared clinical outcomes between 233 obese and non-obese patients receiving cefazolin for MSSA BSI. No significant differences were found in clinical success (81.9% vs 82.7%), mortality (7.2% vs 5.3%), or adverse events (3.6% vs 3.3%). However, obese patients took longer to clear blood cultures (4.62 vs 4.01 days,\n              <jats:italic>P<\/jats:italic>\n              = 0.017).\n            <\/jats:p>\n          <\/jats:sec>","DOI":"10.1128\/aac.00752-24","type":"journal-article","created":{"date-parts":[[2024,9,26]],"date-time":"2024-09-26T13:01:36Z","timestamp":1727355696000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":0,"title":["Impact of obesity on clinical outcomes of methicillin-susceptible\n            <i>Staphylococcus aureus<\/i>\n            bloodstream infections"],"prefix":"10.1128","volume":"68","author":[{"given":"Anthony S.","family":"Wasielewski","sequence":"first","affiliation":[{"name":"UF Health Jacksonville Department of Pharmacy, Jacksonville, Florida, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anthony M.","family":"Casapao","sequence":"additional","affiliation":[{"name":"UF College of Pharmacy, Jacksonville, Florida, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4948-4320","authenticated-orcid":true,"given":"Christopher A.","family":"Jankowski","sequence":"additional","affiliation":[{"name":"UF Health Jacksonville Department of Pharmacy, Jacksonville, Florida, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carmen L.","family":"Isache","sequence":"additional","affiliation":[{"name":"UF Health Jacksonville Department of Medicine, Jacksonville, Florida, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Malleswari","family":"Ravi","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, University of Florida COM-Jacksonville, Jacksonville, Florida, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4891-8625","authenticated-orcid":false,"given":"Ashlan J.","family":"Kunz Coyne","sequence":"additional","affiliation":[{"name":"UF Health Jacksonville Department of Pharmacy, Jacksonville, Florida, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_1_2_2","unstructured":"CDC. 2022. Obesity is a common serious and costly disease. Available from: https:\/\/www.cdc.gov\/obesity\/data\/adult.html. Retrieved 23 Apr 2024."},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMsa1909301"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofaa545"},{"key":"e_1_3_1_5_2","unstructured":"Obesity and infectious diseases: pathophysiology and epidemiology of a double pandemic condition. International Journal of Obesity. Available from: https:\/\/www.nature.com\/articles\/s41366-021-01035-6. 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