{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T02:40:17Z","timestamp":1792118417338,"version":"4.4.0"},"reference-count":21,"publisher":"American Society for Microbiology","issue":"5","license":[{"start":{"date-parts":[[2010,5,1]],"date-time":"2010-05-01T00:00:00Z","timestamp":1272672000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2010,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            The\n            <jats:italic>Capnocytophaga sputigena<\/jats:italic>\n            isolate NOR, responsible for septicemia, was resistant to amoxicillin and narrow-spectrum cephalosporins. In a cloning experiment, a new gene,\n            <jats:italic>bla<\/jats:italic>\n            <jats:sub>CSP-1<\/jats:sub>\n            , was identified; this gene encodes a novel extended-spectrum \u03b2-lactamase (ESBL) that shares only 52% and 49% identities with the CME-1 and VEB-1 \u03b2-lactamases, respectively. The G+C content of this gene, its genetic environment, the absence of conjugation transfer, and its detection in two reference strains suggested that it was an intrinsic resistance gene located on the chromosome.\n          <\/jats:p>","DOI":"10.1128\/aac.00791-09","type":"journal-article","created":{"date-parts":[[2010,3,23]],"date-time":"2010-03-23T01:42:20Z","timestamp":1269308540000},"page":"2231-2234","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":29,"title":["Characterization of CSP-1, a Novel Extended-Spectrum \u03b2-Lactamase Produced by a Clinical Isolate of\n            <i>Capnocytophaga sputigena<\/i>"],"prefix":"10.1128","volume":"54","author":[{"given":"He\u0301le\u0300ne","family":"Guillon","sequence":"first","affiliation":[{"name":"Service de Bacte\u0301riologie, Centre Hospitalo-Universitaire d'Amiens, Ho\u0302pital Nord, Faculte\u0301 de Me\u0301decine d'Amiens, Universite\u0301 de Picardie Jules Verne, 80000 Amiens, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franc\u0327ois","family":"Eb","sequence":"additional","affiliation":[{"name":"Service de Bacte\u0301riologie, Centre Hospitalo-Universitaire d'Amiens, Ho\u0302pital Nord, Faculte\u0301 de Me\u0301decine d'Amiens, Universite\u0301 de Picardie Jules Verne, 80000 Amiens, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hedi","family":"Mammeri","sequence":"additional","affiliation":[{"name":"Service de Bacte\u0301riologie, Centre Hospitalo-Universitaire d'Amiens, Ho\u0302pital Nord, Faculte\u0301 de Me\u0301decine d'Amiens, Universite\u0301 de Picardie Jules Verne, 80000 Amiens, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1042\/bj2760269"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.40.3.616"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.44.1.1-9.2000"},{"key":"e_1_3_1_5_2","unstructured":"Performance standards for antimicrobial susceptibility testing: twentieth informational supplement. 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First case of bacteriemia due to chromosome-encoded CfxA3-\u03b2-lactamase-producing Capnocytophaga sputigena in a pediatric patient with acute erythroblastic leukemia. Eur. J. Med. Res.13:133-135.","journal-title":"Eur. J. Med. 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