{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T19:52:52Z","timestamp":1791834772248,"version":"4.3.4"},"reference-count":18,"publisher":"American Society for Microbiology","issue":"10","license":[{"start":{"date-parts":[[2024,10,8]],"date-time":"2024-10-08T00:00:00Z","timestamp":1728345600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/doi.org\/10.1128\/ASMCopyrightv2"},{"start":{"date-parts":[[2024,10,8]],"date-time":"2024-10-08T00:00:00Z","timestamp":1728345600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2024,10,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:sec>\n            <jats:title\/>\n            <jats:p>This study investigated the real-world incidence rate of serotonin syndrome in patients receiving tedizolid and concomitant serotonergic agents. A retrospective cohort of 479 adult patients was assessed between January 2015 and July 2023. Overall, a rare rate of 0.4% (2\/479) of possible serotonin syndrome with tedizolid was identified. Given that concomitant serotonergic agents were commonly used, further study is warranted to determine causality.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1128\/aac.00870-24","type":"journal-article","created":{"date-parts":[[2024,9,5]],"date-time":"2024-09-05T13:18:29Z","timestamp":1725542309000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":5,"title":["Incidence of serotonin syndrome in patients receiving tedizolid and concomitant serotonergic agents"],"prefix":"10.1128","volume":"68","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-7304-3543","authenticated-orcid":true,"given":"Yingsi","family":"Fang","sequence":"first","affiliation":[{"name":"Department of Pharmacy, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lloyd G.","family":"Clarke","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA"},{"name":"Antibiotic Management Program, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brandon J.","family":"Smith","sequence":"additional","affiliation":[{"name":"Antibiotic Management Program, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA"},{"name":"Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8873-1451","authenticated-orcid":true,"given":"Sunish","family":"Shah","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA"},{"name":"Antibiotic Management Program, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00431-13"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2013.241"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(14)70737-6"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.3390\/pharmacy6020043"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.18773\/austprescr.2016.039"},{"key":"e_1_3_1_7_2","unstructured":"FDA drug safety communication: serious CNS reactions possible when linezolid (Zyvox) is given to patients taking certain psychiatric medications. 2011. FDA. Available from: https:\/\/www.fda.gov\/drugs\/drug-safety-and-availability\/fda-drug-safety-communication-serious-cns-reactions-possible-when-linezolid-zyvox-given-patients#table. Retrieved 24 Sep 2023."},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00228-020-02990-1"},{"key":"e_1_3_1_9_2","doi-asserted-by":"publisher","DOI":"10.1093\/qjmed\/hcg109"},{"key":"e_1_3_1_10_2","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.148.6.705"},{"key":"e_1_3_1_12_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cit616"},{"key":"e_1_3_1_14_2","doi-asserted-by":"publisher","DOI":"10.1345\/aph.1R386"},{"key":"e_1_3_1_15_2","doi-asserted-by":"publisher","DOI":"10.1097\/JCP.0000000000000751"},{"key":"e_1_3_1_16_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2022.47426"},{"key":"e_1_3_1_17_2","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofw172.440"},{"key":"e_1_3_1_18_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00356-20"},{"key":"e_1_3_1_19_2","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofac028"},{"key":"e_1_3_1_20_2","doi-asserted-by":"publisher","DOI":"10.1136\/ejhpharm-2018-001752"},{"key":"e_1_3_1_21_2","first-page":"E27","article-title":"Incidence of serotonin syndrome in patients treated with fentanyl on serotonergic agents","volume":"18","author":"Koury KM","year":"2015","unstructured":"Koury KM, Tsui B, Gulur P. 2015. Incidence of serotonin syndrome in patients treated with fentanyl on serotonergic agents. Pain Physician 18:E27\u201330.","journal-title":"Pain Physician"}],"container-title":["Antimicrobial Agents and Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/aac.00870-24","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/aac.00870-24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,8]],"date-time":"2024-10-08T15:47:36Z","timestamp":1728402456000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/aac.00870-24"}},"subtitle":[],"editor":[{"given":"Pranita D.","family":"Tamma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2024,10,8]]},"references-count":18,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2024,10,8]]}},"alternative-id":["10.1128\/aac.00870-24"],"URL":"https:\/\/doi.org\/10.1128\/aac.00870-24","relation":{},"ISSN":["0066-4804","1098-6596"],"issn-type":[{"value":"0066-4804","type":"print"},{"value":"1098-6596","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10,8]]},"assertion":[{"value":"2024-06-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-08-16","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-09-05","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e00870-24"}}