{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T15:02:09Z","timestamp":1775055729616,"version":"3.50.1"},"reference-count":43,"publisher":"American Society for Microbiology","issue":"10","license":[{"start":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T00:00:00Z","timestamp":1538352000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2018,10]]},"abstract":"<jats:p>Practitioners commonly use amikacin in patients with cystic fibrosis. Establishment of the pharmacokinetics of amikacin in adults with cystic fibrosis may increase the efficacy and safety of therapy.<\/jats:p>","DOI":"10.1128\/aac.00877-18","type":"journal-article","created":{"date-parts":[[2018,7,31]],"date-time":"2018-07-31T09:58:24Z","timestamp":1533031104000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":20,"title":["Population Pharmacokinetics of Amikacin in Adult Patients with Cystic Fibrosis"],"prefix":"10.1128","volume":"62","author":[{"given":"S\u00edlvia M.","family":"Illamola","sequence":"first","affiliation":[{"name":"Division of Clinical Pharmacology, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, Utah, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hoa Q.","family":"Huynh","sequence":"additional","affiliation":[{"name":"University of Utah College of Pharmacy, Salt Lake City, Utah, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoxi","family":"Liu","sequence":"additional","affiliation":[{"name":"Division of Clinical Pharmacology, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, Utah, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zubin N.","family":"Bhakta","sequence":"additional","affiliation":[{"name":"The Adult Cystic Fibrosis Center, University of Utah, Salt Lake City, Utah, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catherine M.","family":"Sherwin","sequence":"additional","affiliation":[{"name":"Division of Clinical Pharmacology, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, Utah, USA"},{"name":"University of Utah College of Pharmacy, Salt Lake City, Utah, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0121-4847","authenticated-orcid":false,"given":"Theodore G.","family":"Liou","sequence":"additional","affiliation":[{"name":"The Adult Cystic Fibrosis Center, University of Utah, Salt Lake City, Utah, USA"},{"name":"Division of Respiratory, Critical Care and Occupational Pulmonary Medicine, Department of Internal Medicine, School of Medicine, University of Utah, Salt Lake City, Utah, USA"},{"name":"The Center for Quantitative Biology, University of Utah, Salt Lake City, Utah, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Holly","family":"Carveth","sequence":"additional","affiliation":[{"name":"The Adult Cystic Fibrosis Center, University of Utah, Salt Lake City, Utah, USA"},{"name":"Division of Respiratory, Critical Care and Occupational Pulmonary Medicine, Department of Internal Medicine, School of Medicine, University of Utah, Salt Lake City, Utah, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David C.","family":"Young","sequence":"additional","affiliation":[{"name":"University of Utah College of Pharmacy, Salt Lake City, Utah, USA"},{"name":"The Adult Cystic Fibrosis Center, University of Utah, Salt Lake City, Utah, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinbiochem.2012.05.034"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)60327-5"},{"key":"e_1_3_2_4_2","first-page":"241","article-title":"Pathology of cystic fibrosis review of the literature and comparison with 146 autopsied cases","volume":"2","author":"Oppenheimer EH","year":"1975","unstructured":"Oppenheimer EH, Esterly JR. 1975. Pathology of cystic fibrosis review of the literature and comparison with 146 autopsied cases. Perspect Pediatr Pathol 2:241\u2013278.","journal-title":"Perspect Pediatr Pathol"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.4187\/aarc0443"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199607183350307"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200812-1845PP"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.21198"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1186\/cc12844"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/s002280050389"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2125.2005.02530.x"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.2174\/187231208786734157"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00228-009-0637-4"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.2165\/11595640-000000000-00000"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.burns.2013.06.015"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1097\/BCR.0000000000000159"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1111\/bcp.13016"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1472-8206.1995.tb00266.x"},{"key":"e_1_3_2_19_2","first-page":"24","article-title":"Population pharmacokinetics of amikacin in geriatric patients studied with the NPEM-2 algorithm","volume":"35","author":"Debord J","year":"1997","unstructured":"Debord J, Charmes JP, Marquet P, Merle L, Lachatre G. 1997. Population pharmacokinetics of amikacin in geriatric patients studied with the NPEM-2 algorithm. Int J Clin Pharmacol Ther 35:24\u201327.","journal-title":"Int J Clin Pharmacol Ther"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007691-199706000-00005"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.2165\/00044011-199815050-00008"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.42.4.849"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF03190009"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/44.2.235"},{"key":"e_1_3_2_25_2","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1345\/aph.19104","article-title":"Bayesian approach to control of amikacin serum concentrations in critically ill patients with sepsis","volume":"34","author":"Lugo-Goytia G","year":"2000","unstructured":"Lugo-Goytia G, Castaneda-Hernandez G. 2000. Bayesian approach to control of amikacin serum concentrations in critically ill patients with sepsis. Ann Pharmacother 34:1389\u20131394.","journal-title":"Ann Pharmacother"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1097\/FTD.0b013e3181f675c2"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.5414\/CP201520"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/202818"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00228-014-1766-y"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2015.06.008"},{"key":"e_1_3_2_31_2","doi-asserted-by":"crossref","first-page":"35S","DOI":"10.1111\/j.1365-2125.2001.00377.x","article-title":"The therapeutic monitoring of antimicrobial agents","volume":"52","author":"Begg EJ","year":"2001","unstructured":"Begg EJ, Barclay ML, Kirkpatrick CM. 2001. The therapeutic monitoring of antimicrobial agents. Br J Clin Pharmacol 52(Suppl 1):35S\u201343S.","journal-title":"Br J Clin Pharmacol"},{"key":"e_1_3_2_32_2","doi-asserted-by":"publisher","DOI":"10.2165\/00003088-199835040-00004"},{"key":"e_1_3_2_33_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-100-3-352"},{"key":"e_1_3_2_34_2","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.22655"},{"key":"e_1_3_2_35_2","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.22669"},{"key":"e_1_3_2_36_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(82)80663-X"},{"key":"e_1_3_2_37_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(84)80375-3"},{"key":"e_1_3_2_38_2","doi-asserted-by":"publisher","DOI":"10.1038\/clpt.1984.187"},{"key":"e_1_3_2_39_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01477-06"},{"key":"e_1_3_2_40_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkt035"},{"key":"e_1_3_2_41_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007691-199404000-00003"},{"key":"e_1_3_2_42_2","doi-asserted-by":"publisher","DOI":"10.1159\/000180580"},{"key":"e_1_3_2_43_2","doi-asserted-by":"crossref","first-page":"1575","DOI":"10.1093\/clinchem\/27.9.1575","article-title":"Fluorescence polarization immunoassay. iii. An automated system for therapeutic drug determination","volume":"27","author":"Jolley ME","year":"1981","unstructured":"Jolley ME, Stroupe SD, Schwenzer KS, Wang CJ, Lu-Steffes M, Hill HD, Popelka SR, Holen JT, Kelso DM. 1981. Fluorescence polarization immunoassay. iii. An automated system for therapeutic drug determination. Clin Chem 27:1575\u20131579.","journal-title":"Clin Chem"},{"key":"e_1_3_2_44_2","volume-title":"Division of Pharmacology","author":"Beal SL","year":"1998","unstructured":"Beal SL, Boeckman AJ, Sheiner LB. 1998. NONMEM user guides. Division of Pharmacology, University of California, San Francisco, San Francisco, CA."}],"container-title":["Antimicrobial Agents and Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.00877-18","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.00877-18","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,8]],"date-time":"2024-07-08T20:31:05Z","timestamp":1720470665000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/AAC.00877-18"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10]]},"references-count":43,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2018,10]]}},"alternative-id":["10.1128\/AAC.00877-18"],"URL":"https:\/\/doi.org\/10.1128\/aac.00877-18","relation":{},"ISSN":["0066-4804","1098-6596"],"issn-type":[{"value":"0066-4804","type":"print"},{"value":"1098-6596","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,10]]},"assertion":[{"value":"2018-04-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-07-25","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-09-24","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e00877-18"}}