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This study aims to investigate the pharmacodynamics of different simulated intravenous amikacin doses on susceptible\n            <jats:named-content content-type=\"genus-species\">P. aeruginosa<\/jats:named-content>\n            to inform ventilator-associated pneumonia (VAP) and sepsis treatment choices. A hollow-fiber infection model with two\n            <jats:named-content content-type=\"genus-species\">P. aeruginosa<\/jats:named-content>\n            isolates (MICs of 2 and 8\u2009mg\/liter) with an initial inoculum of \u223c10\n            <jats:sup>8<\/jats:sup>\n            CFU\/ml was used to test different amikacin dosing regimens.\n          <\/jats:p>","DOI":"10.1128\/aac.00879-20","type":"journal-article","created":{"date-parts":[[2020,7,8]],"date-time":"2020-07-08T13:21:22Z","timestamp":1594214482000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":10,"title":["Pharmacodynamic Evaluation of Plasma and Epithelial Lining Fluid Exposures of Amikacin against Pseudomonas aeruginosa in a Dynamic\n            <i>In Vitro<\/i>\n            Hollow-Fiber Infection Model"],"prefix":"10.1128","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7929-9812","authenticated-orcid":false,"given":"Aaron 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