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Selected isolates were identified by sequencing of the 16S rRNA and<jats:italic>rpoB<\/jats:italic>genes. PCR and cloning experiments were used to identify broad-spectrum-\u03b2-lactamase-encoding genes and their genetic context. Clavulanic acid-inhibited extended-spectrum-\u03b2-lactamase (ESBL) genes were identified in 71% of the<jats:italic>Aeromonas<\/jats:italic>sp. isolates. A variety of ESBL genes were detected, including<jats:italic>bla<\/jats:italic><jats:sub>VEB-1a<\/jats:sub>,<jats:italic>bla<\/jats:italic><jats:sub>SHV-12<\/jats:sub>,<jats:italic>bla<\/jats:italic><jats:sub>PER-1<\/jats:sub>,<jats:italic>bla<\/jats:italic><jats:sub>PER-6<\/jats:sub>,<jats:italic>bla<\/jats:italic><jats:sub>TLA-2<\/jats:sub>, and<jats:italic>bla<\/jats:italic><jats:sub>GES-7<\/jats:sub>, suggesting an aquatic reservoir of those ESBL genes. Moreover, the repeated elements and different insertion sequences were identified in association with the<jats:italic>bla<\/jats:italic><jats:sub>PER-6<\/jats:sub>and the<jats:italic>bla<\/jats:italic><jats:sub>VEB-1a<\/jats:sub>genes, respectively, indicating a wide diversity of mobilization events, making<jats:italic>Aeromonas<\/jats:italic>spp. a vehicle for ESBL dissemination.<\/jats:p>","DOI":"10.1128\/aac.00921-10","type":"journal-article","created":{"date-parts":[[2010,12,14]],"date-time":"2010-12-14T04:44:21Z","timestamp":1292301861000},"page":"1256-1261","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":67,"title":["Diversity of Clavulanic Acid-Inhibited Extended-Spectrum \u03b2-Lactamases in<i>Aeromonas<\/i>spp. from the Seine River, Paris, France"],"prefix":"10.1128","volume":"55","author":[{"given":"Delphine","family":"Girlich","sequence":"first","affiliation":[{"name":"Service de Bacte\u0301riologie-Virologie, INSERM U914, Emerging Resistance to Antibiotics, Ho\u0302pital de Bice\u0302tre, Assistance Publique\/Ho\u0302pitaux de Paris, Faculte\u0301 de Me\u0301decine et Universite\u0301 Paris Sud, 94275 Le Kremlin-Bice\u0302tre, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laurent","family":"Poirel","sequence":"additional","affiliation":[{"name":"Service de Bacte\u0301riologie-Virologie, INSERM U914, Emerging Resistance to Antibiotics, Ho\u0302pital de Bice\u0302tre, Assistance Publique\/Ho\u0302pitaux de Paris, Faculte\u0301 de Me\u0301decine et Universite\u0301 Paris Sud, 94275 Le Kremlin-Bice\u0302tre, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrice","family":"Nordmann","sequence":"additional","affiliation":[{"name":"Service de Bacte\u0301riologie-Virologie, INSERM U914, Emerging Resistance to Antibiotics, Ho\u0302pital de Bice\u0302tre, Assistance Publique\/Ho\u0302pitaux de Paris, Faculte\u0301 de Me\u0301decine et Universite\u0301 Paris Sud, 94275 Le Kremlin-Bice\u0302tre, France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1042\/bj2760269"},{"key":"e_1_3_2_3_2","doi-asserted-by":"crossref","first-page":"713","DOI":"10.3201\/eid0807.010264","volume":"8","year":"2002","unstructured":"Ash, R. 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