{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T13:47:15Z","timestamp":1789652835375,"version":"4.0.0"},"reference-count":30,"publisher":"American Society for Microbiology","issue":"11","license":[{"start":{"date-parts":[[2020,10,20]],"date-time":"2020-10-20T00:00:00Z","timestamp":1603152000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"DOI":"10.13039\/501100002855","name":"Ministry of Science and Technology of the People's Republic of China","doi-asserted-by":"publisher","award":["2018ZX10101002-004"],"award-info":[{"award-number":["2018ZX10101002-004"]}],"id":[{"id":"10.13039\/501100002855","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004921","name":"Shanghai Jiao Tong University","doi-asserted-by":"publisher","award":["MMLKF14-03"],"award-info":[{"award-number":["MMLKF14-03"]}],"id":[{"id":"10.13039\/501100004921","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81602904"],"award-info":[{"award-number":["81602904"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2020,10,20]]},"abstract":"<jats:p>\n            Delayed clearance of\n            <jats:named-content content-type=\"genus-species\">Plasmodium falciparum<\/jats:named-content>\n            by artemisinin-based combination therapies (ACTs) has already been observed for African isolates. Here, we aimed to investigate the prevalence, among travelers returning from African countries, of polymorphisms in two genes correlated with delayed parasite clearance (encoding\n            <jats:named-content content-type=\"genus-species\">P. falciparum<\/jats:named-content>\n            Kelch 13 [\n            <jats:italic>PfK13<\/jats:italic>\n            ] and ubiquitin-specific protease 1 [\n            <jats:italic>pfubp1<\/jats:italic>\n            ]) reported in eastern China and to provide baseline data for antimalarial drug resistance (ART) surveillance and evaluation.\n          <\/jats:p>","DOI":"10.1128\/aac.00981-20","type":"journal-article","created":{"date-parts":[[2020,8,24]],"date-time":"2020-08-24T13:32:37Z","timestamp":1598275957000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":9,"title":["Prevalence of Plasmodium falciparum Kelch 13 (\n            <i>PfK13<\/i>\n            ) and Ubiquitin-Specific Protease 1 (\n            <i>pfubp1<\/i>\n            ) Gene Polymorphisms in Returning Travelers from Africa Reported in Eastern China"],"prefix":"10.1128","volume":"64","author":[{"given":"He","family":"Yan","sequence":"first","affiliation":[{"name":"National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Key Laboratory of Parasite and Vector Biology, MOH, WHO Collaborating Centre for Tropical Diseases, National Center for International Research on Tropical Diseases, The School of Global Health, Chinese Center for Tropical Diseases Research, Shanghai Jiao Tong University, School of Medicine, Shanghai, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangli","family":"Kong","sequence":"additional","affiliation":[{"name":"Shandong Institute of Parasitic Diseases, Shandong First Medical University and Shandong Academy of Medical Sciences, Shandong, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Zhang","sequence":"additional","affiliation":[{"name":"Anhui Provincial Center for Disease Control and Prevention, Anhui, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huihui","family":"Xiao","sequence":"additional","affiliation":[{"name":"Changsha Center for Disease Control and Prevention, Hunan, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyu","family":"Feng","sequence":"additional","affiliation":[{"name":"National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Key Laboratory of Parasite and Vector Biology, MOH, WHO Collaborating Centre for Tropical Diseases, National Center for International Research on Tropical Diseases, The School of Global Health, Chinese Center for Tropical Diseases Research, Shanghai Jiao Tong University, School of Medicine, Shanghai, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong","family":"Tu","sequence":"additional","affiliation":[{"name":"National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Key Laboratory of Parasite and Vector Biology, MOH, WHO Collaborating Centre for Tropical Diseases, National Center for International Research on Tropical Diseases, The School of Global Health, Chinese Center for Tropical Diseases Research, Shanghai Jiao Tong University, School of Medicine, Shanghai, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5798-0797","authenticated-orcid":false,"given":"Jun","family":"Feng","sequence":"additional","affiliation":[{"name":"National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Key Laboratory of Parasite and Vector Biology, MOH, WHO Collaborating Centre for Tropical Diseases, National Center for International Research on Tropical Diseases, The School of Global Health, Chinese Center for Tropical Diseases Research, Shanghai Jiao Tong University, School of Medicine, Shanghai, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-800869-0.00009-3"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.12140\/j.issn.1000-7423.2019.03.001"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.30875\/7e6f8c91-en"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature12876"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1314981"},{"key":"e_1_3_3_7_2","volume-title":"Accelerating malaria elimination in the Greater Mekong Subregion","author":"World Health Organization","year":"2018","unstructured":"World Health Organization. 2018. Accelerating malaria elimination in the Greater Mekong Subregion. World Health Organization, Geneva, Switzerland. https:\/\/www.who.int\/malaria\/areas\/greater_mekong\/overview\/en\/."},{"key":"e_1_3_3_8_2","volume-title":"Artemisinin resistance and artemisinin-based combination therapy efficacy: status report","author":"World Health Organization","year":"2018","unstructured":"World Health Organization. 2018. Artemisinin resistance and artemisinin-based combination therapy efficacy: status report. World Health Organization, Geneva, Switzerland. https:\/\/apps.who.int\/iris\/handle\/10665\/274362?search-result=true&query=Artemisinin+and+artemisinin-based+combination+therapy+resistance&scope=&rpp=10&sort_by=score&order=desc."},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid2208.160004"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(15)70032-0"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1513137"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2019.00095"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12936-020-3140-0"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc1612765"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiu358"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13071-018-2762-3"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0504842102"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.2007.05753.x"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1038\/srep03318"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tmaid.2019.101505"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12936-018-2444-9"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0808859"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.04843-14"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0213686"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.04144-14"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00552-19"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.17-0864"},{"key":"e_1_3_3_28_2","doi-asserted-by":"crossref","first-page":"P87","DOI":"10.1186\/1475-2875-13-S1-P87","article-title":"Large differences in variability for genes associated with antimalarial drug resistance between samples from Tanzania and Ethiopia","volume":"13","author":"Lemu G","year":"2014","unstructured":"Lemu G, Nizar E, G\u00f6te S, Erasmus K, Angel C. 2014. 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National Health Commission, Beijing, China."}],"container-title":["Antimicrobial Agents and Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.00981-20","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/AAC.00981-20","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,21]],"date-time":"2022-02-21T21:34:49Z","timestamp":1645479289000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/AAC.00981-20"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10,20]]},"references-count":30,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2020,10,20]]}},"alternative-id":["10.1128\/AAC.00981-20"],"URL":"https:\/\/doi.org\/10.1128\/aac.00981-20","relation":{},"ISSN":["0066-4804","1098-6596"],"issn-type":[{"value":"0066-4804","type":"print"},{"value":"1098-6596","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,10,20]]},"assertion":[{"value":"2020-05-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-08-10","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-10-20","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e00981-20"}}