{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T09:46:34Z","timestamp":1790934394384,"version":"4.1.0"},"reference-count":42,"publisher":"American Society for Microbiology","issue":"11","license":[{"start":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T00:00:00Z","timestamp":1762300800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T00:00:00Z","timestamp":1762300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Antimicrob Agents Chemother"],"published-print":{"date-parts":[[2025,11,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title\/>\n                    <jats:p>\n                      <jats:italic toggle=\"yes\">Lomentospora prolificans<\/jats:italic>\n                      is a multi-drug-resistant filamentous fungus that can cause invasive disease in both immunocompromised and immunocompetent hosts. Current treatment options are limited. Olorofim is an investigational antifungal that demonstrates activity against several different molds, including many that are resistant to other antifungals. The case presented by Fortini et al. (Antimicrob Agents Chemother 69:e00602-25, 2025,\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/doi.org\/10.1128\/aac.00602-25\" xlink:type=\"simple\">https:\/\/doi.org\/10.1128\/aac.00602-25<\/jats:ext-link>\n                      ) describes the successful use of olorofim treatment in an 8-year-old who suffered from\n                      <jats:italic toggle=\"yes\">Lomentospora prolificans<\/jats:italic>\n                      tendonitis, synovitis, and osteomyelitis.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1128\/aac.01072-25","type":"journal-article","created":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T15:49:14Z","timestamp":1758901754000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":2,"title":["Case Commentary: Successful use of olorofim for the treatment of multi-drug-resistant\n                    <i>Lomentospora prolificans<\/i>\n                    infection in a child"],"prefix":"10.1128","volume":"69","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2225-5122","authenticated-orcid":true,"given":"Nathan P.","family":"Wiederhold","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/01kd65564","id-type":"ROR","asserted-by":"publisher"}],"name":"Fungus Testing Laboratory, Department of Pathology and Laboratory Medicine, University of Texas Science Center at San Antonio","place":["San Antonio, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1128\/aac.00602-25"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.5962\/p.417593"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.5962\/p.418847"},{"key":"e_1_3_1_5_2","first-page":"3","article-title":"Taxonomy of the medical species of Pseudallescheria and Scedosporium","volume":"1","author":"Gueho E","year":"1991","unstructured":"Gueho E, Hoog GS. 1991. 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