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Peak plasma rifaximin concentrations were low after nine consecutive doses, and no accumulation was observed. Rifaximin serum levels were minimal and similar to those previously reported in studies of healthy volunteers.\n          <\/jats:p>","DOI":"10.1128\/aac.01108-07","type":"journal-article","created":{"date-parts":[[2007,12,18]],"date-time":"2007-12-18T02:39:01Z","timestamp":1197945541000},"page":"1179-1181","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":28,"title":["Systemic Pharmacokinetics of Rifaximin in Volunteers with Shigellosis"],"prefix":"10.1128","volume":"52","author":[{"given":"David N.","family":"Taylor","sequence":"first","affiliation":[{"name":"Center for Immunization Research, Department of International Health, The Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland"},{"name":"Salix Pharmaceuticals, Inc., Morrisville, North Carolina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robin","family":"McKenzie","sequence":"additional","affiliation":[{"name":"Center for Immunization Research, Department of International Health, The Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Durbin","sequence":"additional","affiliation":[{"name":"Center for Immunization Research, Department of International Health, The Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Colleen","family":"Carpenter","sequence":"additional","affiliation":[{"name":"Center for Immunization Research, Department of International Health, The Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Haake","sequence":"additional","affiliation":[{"name":"Salix Pharmaceuticals, Inc., Morrisville, North Carolina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. 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